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治疗气虚血瘀证中成药的组方规律分析

何浩强 高嘉良 陈光 刘超 王阶

中国药房2017,Vol.28Issue(35):4910-4914,5.
中国药房2017,Vol.28Issue(35):4910-4914,5.DOI:10.6039/j.issn.1001-0408.2017.35.04

治疗气虚血瘀证中成药的组方规律分析

Analysis of the Regularity of Chinese Patent Medicine Prescriptions for the Qi Deficiency and Blood Stasis Syndrome

何浩强 1高嘉良 2陈光 1刘超 1王阶2

作者信息

  • 1. 中国中医科学院广安门医院心血管科,北京 100053
  • 2. 北京中医药大学针灸推拿学院,北京 100029
  • 折叠

摘要

Abstract

OBJECTIVE:To investigate the regularity of Chinese patent medicine prescriptions for Qi deficiency and blood sta-sis syndrome (QDBSS),and to provide reference for studying QDBSS diagnosis standard and new TCM for related symptoms. METHODS:Chinese patent medicine for QDBSS were collected from Chinese Pharmacopoeia (2015 edition) and Chinese Mate-ria Medica Preparation(1993 version). The regularity of Chinese patent medicine prescriptions and symptom association rule were analyzed by using TCM inheritance auxiliary system (V2.5). RESULTS:Among the 171 symptoms,chest tightness,shortness of breath,chest pain,fatigue and palpitation were common symptoms,and three groups of symptoms were included as chest tight-ness-shortness of breath-chest pain-palpitation-irregularly pulse;mouth and eye deviation-numbness of hands and feet-hemiple-gia-stiff tongue-spasm;hypomenorrhea-irregular menstruation-abdominal mass-dysmenorrheal. One hundred and thirty-one Chinese patent medicines included 304 ingredients,top 5 in the list of frequency were Astragalus membranaceus,Salvia militiorrhiza,An-gelica sinensis,Ligusticum chuanxiong,Panax ginseng. A. membranaceus- A. sinensis,L. chuanxiong-A. sinensis,S. militiorrhi-za-A. membranaceus,L. chuanxiong- A. membranaceus and L. chuanxiong-S. militiorrhiza were frequently used herbal combina-tions. A. membranaceus-A. sinensis-L. chuanxiong-S. militiorrhiza-P. ginseng-Carthamus tinctorius-Panax notoginseng was the core combination. A new prescription for QDBSS was formed (P. ginseng-Radix Paeoniae Rubra-borneol-Gastrodia elata-artificial moschus-Myristica fragrans). CONCLUSIONS:QDBSS has common symptoms which exist in many kinds of diseases,such as chest tightness,chest pain and shortness of breath;it also has the unique symptoms among various diseases. Invigorating Qi and promoting blood circulation is the basic treatment for the QDBSS. It is of significance to pay attention to"supplement by passing, combination of pass and supplement"and combine regulating Qi-flowing method with enriching blood method or aromatic warming method for QDBSS therapy according to the differ-ence of Zhengxie shengshuai.

关键词

气虚血瘀证/中成药/中国药典/中药成方制剂/组方规律

Key words

Qi deficiency and blood stasis syndrome/Chi-nese patent medicine/Chinese Pharmacopoeia/Chinese Mate-ria Medica Preparation/Regularity of prescriptions

分类

医药卫生

引用本文复制引用

何浩强,高嘉良,陈光,刘超,王阶..治疗气虚血瘀证中成药的组方规律分析[J].中国药房,2017,28(35):4910-4914,5.

基金项目

国家自然科学基金资助项目(No.81473561) (No.81473561)

中医药行业科研专项项目(No.201207009) (No.201207009)

中国药房

OA北大核心CSTPCD

1001-0408

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