中国医学科学院学报2017，Vol.39Issue(5)：629-636,8.DOI:10.3881/j.issn.1000-503X.2017.05.006
江苏地区汉族人群23个Y染色体STR基因座的多态性
Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province
马骏 1朱爱华 1石津玮 1金明 1巴华杰 1平智广2
作者信息
- 1. 江苏省常州市公安局物证鉴定所,江苏常州213003
- 2. 郑州大学公共卫生学院卫生统计学教研室,郑州450001
- 折叠
摘要
Abstract
Objective To investigate the polymorphisms of 23 Y-STR loci in a Han population in Jiangsu province.Methods Blood samples were collected from 4821 unrelated healthy Han males in Jiangsu province.DNA templates were amplified by PowerPlex Y23 kit,and the amplification products were detected by 3500xL genetic analyzer.Then,we calculated the allele frequencies and gene diversities respectively,as well as the haplotype frequencies and haplotype diversities.Results The gene diversity of these 23 Y-STR loci ranged 0.4099-0.9696.A total of 4781 haplotypes were detected,of which 4743 were found once.The haplotype diversity was 0.99999812.Conclusion The 23 Y-STR loci used in this study are highly polymorphic in Han individuals in Jiangsu province and therefore suitable for population genetic study and forensic individual identification.关键词
Y染色体/短串联重复序列/遗传多态性Key words
Y chromosome/short tandem repeat/genetic polymorphism分类
生物科学引用本文复制引用
马骏,朱爱华,石津玮,金明,巴华杰,平智广..江苏地区汉族人群23个Y染色体STR基因座的多态性[J].中国医学科学院学报,2017,39(5):629-636,8.
