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声速匹配技术在大鼠肝脏脂肪评价中的应用

苏芳菲 曹邱婷 宿愿 胡向东 赵丽琴 钱林学

中国医学装备2017,Vol.14Issue(12):15-17,3.
中国医学装备2017,Vol.14Issue(12):15-17,3.DOI:10.3969/J.ISSN.1672-8270.2017.12.005

声速匹配技术在大鼠肝脏脂肪评价中的应用

The application of sound speed correction technique in the evaluation of liver fat of rat

苏芳菲 1曹邱婷 2宿愿 1胡向东 1赵丽琴 2钱林学1

作者信息

  • 1. 首都医科大学附属北京友谊医院超声科 北京 100050
  • 2. 首都医科大学附属北京友谊医院放射科 北京 100050
  • 折叠

摘要

Abstract

Objective:To explore the relationship between the fatty liver of different levels and sound velocity, and discuss the feasibility of sound speed correction technique for the grading diagnosis of fatty liver.Methods: 80 SD rats were selected and divided into control group (n=20) and observation group (n=60). Zone speed index (ZSI) was measured and pathological analysis was carried out at different feeding weeks. Depended on the pathological analysis, the observation group was further divided into mild fatty liver group, moderate fatty liver group and severe fatty liver group, and the ZSI value among different groups was statistically analyzed. Results: The ZSI value of the control group was 58.40±2.04, and the ZSI values in mild group, moderate group and severe group were 45.74±6.07, 30.25±7.59 and 6.14±12.31, respectively. And the differences among control group, moderate group and severe group were statistically significant (t=8.892,t=7.075,t=6.889;P<0.05).Conclusion: The sound speed correction technique can be used to classify SD rats with fatty liver.

关键词

声速匹配/脂肪肝/区域速度指数/大鼠

Key words

Sound speed correction/Fatty liver/Zone speed index/Rat

分类

医药卫生

引用本文复制引用

苏芳菲,曹邱婷,宿愿,胡向东,赵丽琴,钱林学..声速匹配技术在大鼠肝脏脂肪评价中的应用[J].中国医学装备,2017,14(12):15-17,3.

基金项目

首都医科大学基础-临床合作基金(17JL41)"基于能谱CT的脂肪肝定量分级标准的多参数实验研究" (17JL41)

中国医学装备

OACSTPCD

1672-8270

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