动物营养学报2017，Vol.29Issue(12)：4295-4300,6.DOI:10.3969/j.issn.1006-267x.2017.12.008
黄酮类化合物的免疫调节作用及机制
Immune Regulation Function of Flavonoids and Its Mechanisms
摘要
Abstract
Flavonoids compounds are widespread in nature and have a variety of biological functions such as anti-inflammatory, antibacterial, antiviral, antitumor, antioxygenation and so on.In recent years, clinical stud-ies and experiments have showed that flavonoids also play an important role in immune regulation.Flavonoids are able to express immune regulation by affecting immune organ, cellular immunity, humoral immunity and nonspecific immunity, and the immune related signal pathways [ nuclear factor-kappa B ( NF-κB) , Toll like receptor and mitogen-activated protein kinase ( MAPK) signaling pathway] .In order to provide research meth-ods and ideas for the research and development of traditional medicineand veterinary clinical immunology and the research of the immune regulation of flavonoids, we reviewed the immune regulation effect and mechanism of flavonoids on animals according to domestic and foreign literatures.关键词
黄酮类化合物/免疫调节/核转录因子-κB/Toll样受体/丝裂原活化蛋白激酶Key words
flavonoids/immune regulation/NF-κB/TLR/MAPK分类
农业科技引用本文复制引用
杨杰,沙金丹,高翔,林思彤,孙婷婷,田春莲,刘明春..黄酮类化合物的免疫调节作用及机制[J].动物营养学报,2017,29(12):4295-4300,6.基金项目
国家自然科学基金(31402252) （31402252）
沈阳农业大学青年基金(20131001) （20131001）
