动物营养学报2017，Vol.29Issue(12)：4578-4587,10.DOI:10.3969/j.issn.1006-267x.2017.12.040
不同水平玉米赤霉烯酮对断奶母仔猪血清酶 、代谢产物和肠道形态的影响
Effects of Different Levels of Zearalenone on Serum Enzymes and Metabolites and Intestinal Morphology of Weaned Gilts
摘要
Abstract
The aim of this study was to investigate the effects of different levels of zearalenone ( ZEA) on ser-um enzymes and metabolites and intestinal morphology of weaned gilts.Forty healthy weaned gilts ( Duroc × Landrace×Yorkshire) aged 28 days with body weight of ( 14.01 ±0.86 ) kg were randomly allocated into 4 groups (10 replicates per group, 1 pig per replicate).Weaned gilts in the control group were fed a basal diet, and those in the experiment groups 1, 2 and 3 were fed ZEA contaminated diet with 0.5, 1.0 and 1.5 mg/kg ZEA supplementation, respectively.The experiment included 10 days pretrial period and then 35 days test peri-od.The results showed as follows:1) compared with the control group, the activities of aspartate aminotrans-ferase , alkaline phosphatase and lactate dehydrogenase in experimental groups were significantly increased ( P<0.05) , serum total cholesterol content in experimental group 2 was significantly increased ( P<0.05) , and the contents of serum urea nitrogen and high-density lipoprotein in experimental group 3 were significantly in-creased ( P<0.05) , while the serum total protein content was significantly decreased ( P<0.05) .2) Compared with the control group, the villus height and crypt depth of duodenum and jejunum in experimental groups were significantly increased ( P<0.05) .In the experimental groups 1 and 2, the ratio of villus height to crypt depth in duodenum was significantly increased (P<0.05), the ratio of villus height to crypt depth in jejunum was significantly decreased ( P<0.05) , and the villus height and the ratio of villus height to crypt depth in jejunum were significantly increased (P<0.05).3) Compared with the control group, the villus height in duodenum of experimental groups was significantly increased, and the arrangement of them were loose and disordered.The number of small intestinal glands was decreased and the mucosal thickness became thinner.4) Compared with the control group, the villus height and the number of small intestinal glands in jejunum of experimental groups was decreased, and the jejunal epithelium of experimental groups 2 and 3 was denuded and the lamina propria was exposed.5) Compared with the control group, the villus height in ileum of experimetal groups 2 and 3 was increased, and the number of diffuse lymphatic cells in the submucosa was increased.Therefore, dietary ZEA (0.5 to 1.5 mg/kg) can change the liver metabolism and intestinal morphology of weaned gilts, thereby affecting the healthy growth of weaned gilts.关键词
断奶母仔猪/玉米赤霉烯酮/血清/肠道形态Key words
weaned gilts/zearalenone/serum/intestinal morphology分类
农业科技引用本文复制引用
程群,姜淑贞,黄丽波,杨维仁,杨立杰,蔡琬婷,廖柔弯..不同水平玉米赤霉烯酮对断奶母仔猪血清酶 、代谢产物和肠道形态的影响[J].动物营养学报,2017,29(12):4578-4587,10.基金项目
山东省现代农业产业技术体系生猪创新团队专项资金( SDAIT-08-05) （ SDAIT-08-05）
国家自然科学基金资助项目( 31572441) （ 31572441）
"双一流"奖补资金资助 （）
