国际医学放射学杂志2017，Vol.40Issue(6)：647-650,655,5.DOI:10.19300/j.2017.L5734zt
急性缺血性脑卒中病人FLAIR血管高信号与预后的相关性研究
Fluid-attenuated inversion recovery vascular hyperintensities and acute ischemic stroke outcome
摘要
Abstract
Objective We investigated whether hyperintense vessels on fluid-attenuated inversion recovery (FLAIR)sequences are associated with stroke outcome.Method Thirty-nine patients with acute ischemic stroke in the emergency green channel in Tiantan Hospital were enrolled including 25 male patients and 14 female patients with the mean age of 59.79±12.99 years.All the patients underwent MR examination including DWI,MRA and FLAIR at baseline,36 completed followup MR examination at 7 days after stroke onset,and 38 cases completed Modified Rankin Scale (mRS) evaluation at 90days.According to the MRA appearance at 7 days,patients were divided into two groups:vascular recanalization group and non-vascular recanalization group.According to the mRS at 90 days,patients were divided into two groups:good outcome group and bad outcome group.We assessed the presence of FLAIR hyperintense vessels (FHV) at the baseline and disappearance of FHV at 7 days.The presence of FHV at the baseline between good and bad outcome groups,the disappearance of FHV between vascular recanalization and non-vascular recanalization groups were compared respectively using Fisher's exact test.Result Among the 36 cases who completed 7-day MRI followup,24 cases presented vascular recanalization.Seventeen of the 18 cases (70.83％) who presented FHV disappearance were in the vascular recanalization group,and 1 of 12case (8.33％) was in non-vascular recanalization group,showing significant difference (P＜0.01).There were 38 cases underwent 90-days followup,29 cases with good outcome and 9 cases with bad outcome.The number of slices showing FHV and modified Alberta Stroke Program Early CT Score (ASPECTS) of FHV at the baseline had no significant difference between good outcome group and bad outcome group (P＞0.05).Conclusion The presence of FHV can not predict clinical outcome at 90 days.However,FHV disappearance in cases with vascular recanalization can be considered as a marker for hemodynamie improvement.关键词
急性缺血性卒中/液体衰减反转恢复/磁共振成像/血管高信号/侧支循环Key words
Acute ischemic stroke/Fluid-attenuated inversion recovery/Magnetic resonance imaging/Hyperintense vessel/Collateral circulation分类
医药卫生引用本文复制引用
荆利娜,高培毅,林燕,隋滨滨,陈丽..急性缺血性脑卒中病人FLAIR血管高信号与预后的相关性研究[J].国际医学放射学杂志,2017,40(6):647-650,655,5.基金项目
“十二五”国家科技支撑计划项目(2011BAI08B09) （2011BAI08B09）
国家自然科学基金(81301193) （81301193）
北京市自然科学基金(7162056,7133238) （7162056,7133238）
国家自然科学基金-NIH国际合作项目(81361120402) （81361120402）
