化工进展2017,Vol.36Issue(12):4586-4591,6.DOI:10.16085/j.issn.1000-6613.2017-0522
Pickering乳液在药物载体制备方面的研究进展
Progress in preparation of drug carriers based on Pickering emulsion
摘要
Abstract
Pickering emulsion is widely used in food,cosmetics and pharmaceutical fields due to its low cost,good stability and low toxicity. Preparation of drug carriers by Pickering emulsion offers great potential in the pharmaceutical industry since the preparation method is simple to operate, improved the dissolution of poorly soluble drugs,and sustained release property. Recent applications of Pickering emulsion in the field of drug carrier are outlined in this review. Firstly,drug delivery systems and properties of Pickering emulsion are briefly introduced. Then drug-carrying microspheres based on Pickering emulsion and stabilized by different solid particles are discussed in detail. In addition,the applications of Pickering emulsion in the preparation of drug-carrying gels,drug-carrying porous scaffolds and drug-carrying emulsions are also discussed. Finally,research directions of drug carriers via the Pickering emulsion are suggested. With the further studies of Pickering emulsion,the stability and biocompatibility of drug carriers can be improved.关键词
Pickering乳液/固体粒子/药物载体/缓释Key words
Pickering emulsion/solid particles/drug carrier/sustained release分类
化学化工引用本文复制引用
戈明亮,汤微..Pickering乳液在药物载体制备方面的研究进展[J].化工进展,2017,36(12):4586-4591,6.基金项目
广东省自然科学基金项目(2016A030313520)及2017年度广东水利科技创新项目(2017-24). (2016A030313520)