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Pickering乳液在药物载体制备方面的研究进展

戈明亮 汤微

化工进展2017,Vol.36Issue(12):4586-4591,6.
化工进展2017,Vol.36Issue(12):4586-4591,6.DOI:10.16085/j.issn.1000-6613.2017-0522

Pickering乳液在药物载体制备方面的研究进展

Progress in preparation of drug carriers based on Pickering emulsion

戈明亮 1汤微1

作者信息

  • 1. 华南理工大学,聚合物成型加工工程教育部重点实验室,聚合物新型成型装备国家工程研究中心,广东广州 510641
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摘要

Abstract

Pickering emulsion is widely used in food,cosmetics and pharmaceutical fields due to its low cost,good stability and low toxicity. Preparation of drug carriers by Pickering emulsion offers great potential in the pharmaceutical industry since the preparation method is simple to operate, improved the dissolution of poorly soluble drugs,and sustained release property. Recent applications of Pickering emulsion in the field of drug carrier are outlined in this review. Firstly,drug delivery systems and properties of Pickering emulsion are briefly introduced. Then drug-carrying microspheres based on Pickering emulsion and stabilized by different solid particles are discussed in detail. In addition,the applications of Pickering emulsion in the preparation of drug-carrying gels,drug-carrying porous scaffolds and drug-carrying emulsions are also discussed. Finally,research directions of drug carriers via the Pickering emulsion are suggested. With the further studies of Pickering emulsion,the stability and biocompatibility of drug carriers can be improved.

关键词

Pickering乳液/固体粒子/药物载体/缓释

Key words

Pickering emulsion/solid particles/drug carrier/sustained release

分类

化学化工

引用本文复制引用

戈明亮,汤微..Pickering乳液在药物载体制备方面的研究进展[J].化工进展,2017,36(12):4586-4591,6.

基金项目

广东省自然科学基金项目(2016A030313520)及2017年度广东水利科技创新项目(2017-24). (2016A030313520)

化工进展

OA北大核心CSCDCSTPCD

1000-6613

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