化工进展2017，Vol.36Issue(z1)：51-57,7.DOI:10.16085/j.issn.1000-6613.2017-0274
微通道并行模块化设计制造及规模化制备功能材料
Modularized microchannel parallelization design and fabrication for mass production of functional materials
摘要
Abstract
Advanced material synthesized from microfluidic technology has been largely restrained into the scale of laboratory study,hindering its large scale industrial application.Here,based on channel parallelization concept with numbering up principle,microfluidic large-scale module of eight channels was designed.The module consists of distribution layers for two phases and droplet generation layer under different planes.The module was fabricated with PMMA substrate using laser microfabrication engraving equipment,achieving the large-scale production of uniform droplets.The flow rates of two phases were investigated on the droplets formation of parallelized channels with scaling effect resulting from the significant problem of fluid distribution.Experimental comparison of two arrays showed the circular array with symmetrical arrangement improved the size uniformity of 42.4% compared to the parallel array.Widely applied functional chitosan microspheres were also mass-synthesized with an average diameter of 540.59μm and a CV of 2.73%.The throughput was largely improved while maintaining excellent uniformity compared to individual channel.关键词
液滴微流控/微通道并行/放大/模块化设计/功能材料Key words
drop-microfluidics/microchannel parallelization/scale-up/modularization design/functional materials分类
化学化工引用本文复制引用
韩腾腾,张莉,宣晋,董政,徐宏..微通道并行模块化设计制造及规模化制备功能材料[J].化工进展,2017,36(z1):51-57,7.基金项目
上海市科学技术委员会资助材料基因组工程研究院项目(16DZ2260604). （16DZ2260604）
