化工进展2017，Vol.36Issue(z1)：297-302,6.DOI:10.16085/j.issn.1000-6613.2017-0308
静电纺丝乙酸纤维素在生物医药领域的应用研究进展
Progress of the biomedical application of cellulose acetate electrospun fibers
摘要
Abstract
For its good solubility in organic solvents, biocompatibility and biodegradability, cellulose acetate is usually used as the substitutive product of cellulose,and widely applied in the fields of biomedicine, electrochemistry, filtration membrane,etc.This paper describes the method to obtain the functional electrospun cellulose acetate fiber carrying the active ingredient such as enzyme,drug,and cell by using physical blend,coaxial electrospinning,layer-by-layer self-assembly technique,etc.The paper also reveals that the electrospun cellulose acetate fiber has significant advantages for its high porosity,specific surface area and three-dimensional net structure.So it can effectively bind biological groups,control the drug release and promote cell adhesion and growth.Meanwhile,the applications on enzyme immobilization,drug delivery and sustained release,tissue engineering,biosensors,antibacterial mats and wound dressings are reviewed.The paper aims to clarify the scientific value and practical significance of the application of electrospinning cellulose acetate,point out the difficulties in scientific research and industrial production,and prospect the fibers development direction.关键词
静电纺丝/乙酸纤维素/生物医学工程Key words
electrospinning/cellulose acetate/biomedical engineering分类
化学化工引用本文复制引用
薛海龙,李莉莉,张春玲,张万喜,侯甲子,程岩..静电纺丝乙酸纤维素在生物医药领域的应用研究进展[J].化工进展,2017,36(z1):297-302,6.基金项目
国家自然科学基金青年基金(51103058)、吉林省青年基金(201101059)、吉林大学汽车材料教育部重点实验室开放基金(10-450060326014,10-450060501458)及国家留学基金委项目. （51103058）
