环境与职业医学2017，Vol.34Issue(11)：1009-1012,4.DOI:10.13213/j.cnki.jeom.2017.17430
百草枯的神经免疫毒性研究进展
Research progress on neuro-immune toxicity of paraquat
摘要
Abstract
Paraquat is a widely used herbicide with moderate toxicity to human.According to available epidemiological data,paraquat can increase the risk of central nervous system degenerative diseases such as Parkinson's disease by chronic low-dose administration.In this paper,a systematic review summarized the immune response involved in central nervous system injury induced by paraquat,including immune disorder of central nervous system and neuroinflammation induced by paraquat,neuroinflammation development associated with neurological damage induced by paraquat,and neuroinflammation induced by paraquat and regulated by multiple factor networks,aiming to provide a theoretical basis for further study of the mechanism of neuro-immune toxicity of paraquat and future drug intervention.关键词
百草枯/小胶质细胞/神经毒性/免疫反应Key words
paraquat/microglia/neurotoxicity/immune response分类
医药卫生引用本文复制引用
杨正丽,张玉彬,周志俊..百草枯的神经免疫毒性研究进展[J].环境与职业医学,2017,34(11):1009-1012,4.基金项目
国家自然科学基金(编号:81673202) （编号:81673202）
