骨髓间充质干细胞在角膜损伤修复中的应用和研究进展OA北大核心CSTPCD
Application and research progress of bone marrow mesenchymal stem cells in corneal injury repair
骨髓间充质干细胞(bone marrow mesenchymal stem cell,BMSC)可在体内外培养诱导分化为角膜上皮细胞、角膜缘上皮细胞和角膜基质细胞等.BMSC移植后可分化为角膜上皮细胞,有效修复损伤的角膜上皮细胞组织,能表达多种细胞因子,减少炎症细胞浸润,减轻细胞损伤,并抑制细胞凋亡,降低角膜移植后的排斥反应;BMSC还能分化促进角膜缘干细胞增殖.也可在载体上利用BMSC构建生物角膜,进行眼表修复,此为基础研究提供了新的研究方向,…查看全部>>
Bone marrow mesenchymal stem cells (BMSCs) are a class of cells that can differentiate into different kind of corneal cells both in vitro and in vivo,which include corneal epithelial cells,limbal epithelial cells and corneal stromal cells.BMSCs could differentiate into corneal epithelial cells after transplantation,which can not only repair the damaged corneal,but also relieve inflammatory injury caused by the inflammatory cell infiltration.The other functio…查看全部>>
董昕;胡竹林
650021 中国云南省昆明市,昆明医科大学第四附属医院眼科云南省第二人民医院眼科中国云南省眼科研究所650021 中国云南省昆明市,昆明医科大学第四附属医院眼科云南省第二人民医院眼科中国云南省眼科研究所
骨髓间充质干细胞角膜损伤与修复研究应用
bone marrow mesenchymal stem cellscorneal injury repairresearchapplication
《国际眼科杂志》 2017 (11)
2060-2064,5
Yunnan Provincial Applied Basic Research Joint Project of Department of Science and Technology and Kunming Medical University (No.2014FB074)云南省科技厅-昆明医科大学应用基础研究联合专项(No.2014FB074)
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