农药学学报2017，Vol.19Issue(6)：665-671,7.DOI:10.16801/j.issn.1008-7303.2017.0090
昆虫γ-氨基丁酸受体竞争性拮抗剂的研究进展
Research progress of insect γ-aminobutyric acid receptor competitive antagonists
摘要
Abstract
γ-Aminobutyric acid (GABA) receptor (GABAR) is an important target of insecticides. Up to date, all the commercially available GABAR-targeting insecticides are GABAR noncompetitive antagonists (NCAs). Competitive antagonists (CAs) of GABARs are potential insecticides, as they have similar functions to NCAs but different binding sites and mechanisms of action. Both CAs and NCAs exhibited insecticidal activities. However, the CA-insecticides are still in the research stage at present. Here, we review the latest research progress of insect GABAR CAs in the recent decade and hope to attract the attention of pesticide researchers.关键词
昆虫/γ-氨基丁酸受体/竞争性拮抗剂/杀虫活性/研究进展Key words
insects/GABA receptors/competitive antagonists/insecticidal activities/research progress分类
农业科技引用本文复制引用
郑小娇,李华光,刘根炎,巨修练..昆虫γ-氨基丁酸受体竞争性拮抗剂的研究进展[J].农药学学报,2017,19(6):665-671,7.基金项目
湖北省教育厅科学技术研究项目(Q20171503) （Q20171503）
武汉工程大学研究生教育创新基金(CX2016081). （CX2016081）
