生物技术通报2017，Vol.33Issue(11)：19-28,10.DOI:10.13560/j.cnki.biotech.bull.1985.2017-0261
植物核苷二磷酸激酶研究进展
Research Advances of NDPKs in Plants
摘要
Abstract
Nucleoside diphosphate kinases (NDPKs) are a class of highly conserved proteins with a size between 70 to 100 kD.They exist as hexamers in most organisms while as tetramers only in few prokaryotes.NDPKs are mainly responsible for keeping the in vivo cellular balance between nucleoside diphosphates and nucleoside triphosphates.Four types of NDPKs,i.e.,NDPK Ⅰ,NDPK Ⅱ,NDPK Ⅱ and NDPK Ⅳ,are found in plants,however,till now researches have been mainly focused on the first three.NDPKIs are found to be involved in plant growth and development,and response to abiotic stress,pathogens and hormones.NDPK Ⅱ s take part in photosynthesis and removal of reactive oxygen species.NDPKⅢs are involved in energy metabolism and programmed cell death.NDPKⅣs are only found in Arabidopsis and rice genomes and predicted to be located in endoplasmic reticulum with unknown function.Besides,NDPKs also display special functions in certain plants,such as DNA replication,starch and cellulose synthesis,auxin signaling and ribozyme activities;however,whether these functions are species-specific needs further study.This article summarizes the phylogenetic analysis and the most recent research progress on biological functions of NDPKs.Finally,the article discusses the prospect of NDPKs research,thus it will facilitate the in-depth and comprehensive study of their function in plants in the future.关键词
核苷二磷酸激酶/NDPK/系统进化/功能Key words
nucleoside diphosphate kinase/NDPK/phylogeny analysis/function引用本文复制引用
朱馨妮,汪珊珊,周佳琴,朱世华..植物核苷二磷酸激酶研究进展[J].生物技术通报,2017,33(11):19-28,10.基金项目
国家自然科学基金项目(31371595) （31371595）
