现代检验医学杂志2017，Vol.32Issue(6)：118-121,4.DOI:10.3969/j.issn.1671-7414.2017.06.034
西安地区妇科患者阴道分泌物支原体检测及耐药性分析
Detection and Drug Resistance of Mycoplasma in Vaginal Secretions of Gynecological Patients in Xi'an
摘要
Abstract
Objective To explore the infection and drug sensitivity of ureaplasma urealyticum(Uu)and mycoplasma hominis (Mh)in vaginal secretion of gynecological outpatients.Methods The infection and drug sensitivity test of Uu and Mh in va-ginal secretion samples of 1 800 patients collected from January 2015 to April 2016 were detected with mycoplasma culture i-dentification and counting drug sensitivity kit produced by Zhengzhou Antu Luke Bioengineering Co.,Ltd.Results The positive rate of Uu(57.27%)was significantly higher than that of Mh(2.78%,χ2=33.69,P<0.001).The positive rate of mycoplasma was highest in the age group of 31~35(77.09%),but that of Uu was highest in the age group of 21~25 (65.83%)and that of Mh in 36~40 years old group(9.09%),in addition that of multiple infection by Uu and Mh was highest in less than 20 years old group(20.51%).There were statistical difference for Un,Mh and co-infection by Un and Mh between age groups(χ2=15.505~36.574,P<0.01).The top three drugs sensitive for mycoplasma were josamycin, minocycline and doxycycline and that last three ones were clindamycin,thiamphenicol and sparfloxacin.The drug sensitive rates for 12 antibiotics against Uu were higher than those against co-infection by Uu and Mh,but those of erythromycin,gat-ifloxacin,azithromycin,clarithromycin and Luo Hongmei against Mh were lower than those against co-infecion of Uu and Mh.Conclusion The detection of mycoplasma and drug sensitivity in vaginal secretions provides the experimental basis for clinical diagnosis and treatment.关键词
阴道分泌物/解脲支原体/人型支原体/药敏试验Key words
vaginal secretion/ureaplasma urealyticum/mycoplasma hominis/drug sensitivity test分类
医药卫生引用本文复制引用
解娟,刘文康,李博,范云,陈红男,李玲..西安地区妇科患者阴道分泌物支原体检测及耐药性分析[J].现代检验医学杂志,2017,32(6):118-121,4.基金项目
国家自然科学基金资助项目(NO.81272856). （NO.81272856）
