实用医学杂志2017，Vol.33Issue(21)：3570-3573,4.DOI:10.3969/j.issn.1006-5725.2017.21.018
血浆NT-proBNP与哮喘急性发作严重程度的相关性
Correlation between plasma NT-proBNP level and the severity of acute asthmatic attack
摘要
Abstract
Objective To investigate the relationship between the plasma NT-proBNP level and the severity of acute asthmatic attack,and to provide a reference for the assessment of the severity of asthma and the prognosis of patients with acute asthmatic attack. Methods A total of 103 adult patients with mild,moderate,severe,and very severe acute asthmatic attack were enrolled in this study. The difference of plasma NT-proBNP level among groups,and the correlation between plasma NT-proBNP level and APACHE II score(Acute Physiology and Chron-ic Health Evaluation)were investigated.The correlation between plasma NT-proBNP level and Peak Expiratory Flow (PEF)was also studied in each group. Results There was significant difference in plasma NT-proBNP among groups(P < 0.05). Plasma NT-proBNP and APACHE II score was positive correlated(R = 0.767 1,P < 0.05). However,plasma NT-proBNP was negatively correlated with PEF(R =-0.709 7,P < 0.05). Conclusion NT-proBNP can be used as one of the indexes to evaluate the severity of acute asthmatic attack.关键词
N-末端脑钠肽前体/哮喘急性发作/急性生理与慢性健康评分/呼气峰值流速Key words
NT-proBNP/acute asthmatic attack/APACHEⅡ/PEF引用本文复制引用
赵展庆,王成存,周小敏,赖震宇,李川..血浆NT-proBNP与哮喘急性发作严重程度的相关性[J].实用医学杂志,2017,33(21):3570-3573,4.基金项目
海南省自然科学基金资助项目(编号:817402) （编号:817402）
海南省卫生计生行业科研项目(编号:16A200098) （编号:16A200098）
