天津中医药2017，Vol.34Issue(12)：845-848,4.DOI:10.11656/j.issn.1672-1519.2017.12.15
北细辛根化学成分研究
Chemical constituents from the roots of Asarum heterotroprides var. mandshuricum
摘要
Abstract
[Objective] To investigate the chemical constituents from the alcohol fraction of the roots of Asarum heterotroprides var. Mandshuricum. [Methods] Column chromatographies of silica gel, preparative HPLC and Sephadex LH-20 are applied to isolate the chemical constituents. Pure compounds were elucidated by means of 1H NMR, 13C NMR and LC-MS. [Results] Fifteen compounds were isolated and identified as (1R, 2S, 5R, 6R)-5′-O-methylpluviatilol, methyl caffeate, (2E, 4E, 8E)-N-isobutyl-2, 4, 8-decatrienamide, cimi-cifugic acid, (1S, 4S, 5S)-5-isopropyl-2-methyl-2-cyclohxene-1, 4-diol, (±)-asarinol A, p-hydroxybenzaldehyde, 3-methoxy-4-hydroxyben-zoic acid, 4-hydroxyphenethyl alcohol, p-hydroxycinnamic acid,β-sitosterol, L-asarinin, piperonylic acid, kakuol and 3, 4-dimethoxycin-namylic alcohol. [Conclusion] Compounds 1~10 were obtainted from Asarum heterotroprides var. mandshuricum for the first time.关键词
北细辛/化学成分/结构鉴定Key words
Asarum heterotroprides var. mandshuricum/chemical constituent/structure elucidation分类
医药卫生引用本文复制引用
董玉启,于华,王春华,李正,朱彦..北细辛根化学成分研究[J].天津中医药,2017,34(12):845-848,4.基金项目
国家自然科学基金青年项目(81403059),天津市科技特派员项目(16JCTPJC49000)和天津市科技计划项目(14TXZYJC00440). （81403059）
