新医学2017，Vol.48Issue(11)：804-807,4.DOI:10.3969/j.issn.0253-9802.2017.11.012
未累及卵巢的盆腔子宫内膜异位病灶电灼术对患者血清AMH水平及卵巢储备功能的影响
Effect of electrocautery of endometriosis without ovary lesions on serum level of anti-Müllerian hormone and ovarian reserve
摘要
Abstract
Objective To evaluate the effect of electrocautery of endometriosis without ovarian lesions upon the serum concentration of anti-Müllerian hormone (AMH) and ovarian reserve.Methods Eighteen patients diagnosed with endometriosis (EMS) without ovarian cyst undergoing electrocautery were selected into the EMS group.During the same period,12 patients without any adverse history of pregnancy receiving laparoscopic myomectomy were assigned into the control group.The AMH levels before,1,3 and 6 months after surgery were statistically compared between the EMS and control groups.The variations in the serum concentrations of luteotropic hormone (LH),follicle-stimulating hormone (FSH) and estradiol between two groups were analyzed before,1,3 and 6 months after surgery.Results No statistical significance was noted in the preoperative AMH levels between two groups (P ＞ 0.05).In the EMS group,the AMH levels at postoperative 1,3 and 6 months were significantly lower compared with those in the control group (all P ＜ 0.05).At postoperative 1 month,the levels of AMH and estradiol were significantly declined,whereas the level of FSH was considerably elevated in the EMS group (both P ＜ 0.008).At postoperative 3 months,the levels of FSH,estradiol and LH in the EMS group were restored to preoperative levels,and tended to stabilize at postoperative 6 months,which did not significantly differ from preoperative levels (all P ＞ 0.008).In the EMS group,the AMH level was not restored at postoperative 3 months,and still significantly lower than preoperative AMH levels (both P ＜ 0.008).Conclusions Electrocautery of endometriosis without ovarian lesions affects the ovarian reserve,which can recover within postoperative 6 months.Compared with FSH,estradiol and LH,AMH is a superior parameter to assess the ovarian reserve.关键词
子宫内膜异位症,盆腔/子宫内膜异位病灶电灼术/抗苗勒管激素/卵巢储备功能Key words
Endometriosis/Electrocautery of endometriosis/Anti-Müllerian hormone/Ovarian reserve引用本文复制引用
李再仪,游泽山,余凤花,邱艺..未累及卵巢的盆腔子宫内膜异位病灶电灼术对患者血清AMH水平及卵巢储备功能的影响[J].新医学,2017,48(11):804-807,4.基金项目
佛山市科技计划基金(2015AB001165) （2015AB001165）
