疑难病杂志2017，Vol.16Issue(12)：1288-1291,4.DOI:10.3969/j.issn.1671-6450.2017.12.028
磷脂酰乙醇胺N-甲基转移酶在肝脏疾病中的作用研究进展
The role of phosphatidylethanolamine N methyltransferase pathway in liver diseases
摘要
Abstract
Phosphatidylethanolamine N methyltransferase(PEMT)can catalyze the conversion of phosphatidylethano-lamine(PE)to phosphatidylcholine(PC).It is involved in a variety of metabolic reactions in liver such as lipid metabolism, endoplasmic reticulum stress and cell autophagy.Recently, more and more studies have shown that aberrant PEMT activity can promote the development of various diseases such as steatohepatitis,liver failure and liver cancer.关键词
磷脂酰乙醇胺氨N-甲基转移酶/非酒精性脂肪肝炎/肝癌/脂质代谢/自噬Key words
Phosphatidylethanolamine N methyltransferase/Nonalcoholic steatohepatitis/Liver cancer/Lipid metabo-lism/Autophagy引用本文复制引用
吴露..磷脂酰乙醇胺N-甲基转移酶在肝脏疾病中的作用研究进展[J].疑难病杂志,2017,16(12):1288-1291,4.基金项目
国家自然科学基金资助项目(8167101437) （8167101437）
