应用化学2017，Vol.34Issue(12)：1355-1369,15.DOI:10.11944/j.issn.1000-0518.2017.12.170302
锌离子荧光探针研究进展
Research Progress of Fluorescent Zinc Probes
摘要
Abstract
It is of great importance to selectively detect and effectively monitor zinc ion because of its wide distribution in human cells and vital roles in human metabolism.Fluorescent probes have been extensively applied in zinc sensing because of the advantages of simple-design, easy-operation, high sensitivity and cell imaging capability.Fluorescent zinc probes are generally constructed based on the mechanisms of photo-induced electron transfer, intra-molecular charge transfer, fluorescence resonance energy transfer, aggregation-induced emission and chelation-enhanced fluorescence.Among these mechanisms, zinc probes constructed on chelation-enhanced fluorescence have the advantages of easy design and synthesis because its fluorophore can simultaneously act as the receptor.In this review, fluorescent zinc probes based on the aforementioned mechanisms, especially, chelation-enhanced fluorescence, reported in recent years are briefly summarized.关键词
锌离子/荧光探针/识别机理/螯合荧光增强/细胞成像Key words
zinc ion/fluorescent probes/sensing mechanism/chelation-enhanced fluorescence/cell imaging分类
化学化工引用本文复制引用
卜露露,王晴,解永树..锌离子荧光探针研究进展[J].应用化学,2017,34(12):1355-1369,15.基金项目
国家自然科学基金项目(21472047,21772041,21702062)、上海市东方学者特聘教授项目(GZ2016006)和中央大学基础研究经费(WK1616004,222201717003,222201714013)资助 Supported by the National Natural Science Fundation of China(No.21472047, No.21772041, No.21702062), the Shanghai Oriental Scholar Distinguished Professor Project(No.GZ2016006), the Central University Basic Research Fellowship(No.WK1616004, No.222201717003, No. 222201714013 ) （21472047,21772041,21702062）
