中国当代儿科杂志2017，Vol.19Issue(12)：1285-1290,6.DOI:10.7499/j.issn.1008-8830.2017.12.012
间充质干细胞源性外泌体在脑损伤治疗中的研究进展
Research advances in mesenchymal stem cell-derived exosomes in treatment of brain injury
摘要
Abstract
Mesenchymal stem cell (MSC) transplantation is considered one of the most promising therapeutic strategies for the repair of brain injuries and plays an important role in various links of nerve repair. Recent studies have shown that MSC-derived exosomes may dominate the repair of brain injuries and help to promote angiogenesis, regulate immunity, inhibit apoptosis, and repair the nerves, and therefore, they have a great potential in the treatment of brain injuries in neonates. With reference to these studies, this article reviews the mechanism of action of exosomes in the repair of brain injuries and related prospects and challenges, in order to provide new directions for the treatment of brain injuries in neonates with stem cells.关键词
间充质干细胞/外泌体/脑损伤/新生儿Key words
Mesenchymal stem cell/Exosome/Brain injury/Neonate引用本文复制引用
岳艳,屈艺..间充质干细胞源性外泌体在脑损伤治疗中的研究进展[J].中国当代儿科杂志,2017,19(12):1285-1290,6.基金项目
国家自然科学基金(81330016,81630038,81771634) （81330016,81630038,81771634）
四川科技厅项目(2016TD0002) （2016TD0002）
国家科技部重大专向(2017 YFA0104200) （2017 YFA0104200）
国家临床重点专科(儿科新生儿专业)建设项目(1311200003303). （儿科新生儿专业）
