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孕前糖尿病致先天性心脏病的机制研究进展

王婕 王凤

中国当代儿科杂志2017,Vol.19Issue(12):1297-1300,4.
中国当代儿科杂志2017,Vol.19Issue(12):1297-1300,4.DOI:10.7499/j.issn.1008-8830.2017.12.014

孕前糖尿病致先天性心脏病的机制研究进展

Research advances in the mechanism of congenital heart disease induced by pregestational diabetes mellitus

王婕 1王凤1

作者信息

  • 1. 复旦大学附属儿科医院心血管科,上海 200032
  • 折叠

摘要

Abstract

Congenital heart disease (CHD) is the most common birth defect at present and has a complex etiology which involves the combined effect of genetic and environmental factors. Pregestational diabetes mellitus is significantly associated with the development of CHD, but the detailed mechanism remains unknown. This article reviews the research advances in the molecular mechanism of CHD caused by pregestational diabetes mellitus.

关键词

孕前糖尿病/先天性心脏病/分子机制

Key words

Pregestational diabetes mellitus/Congenital heart disease/Molecular mechanism

引用本文复制引用

王婕,王凤..孕前糖尿病致先天性心脏病的机制研究进展[J].中国当代儿科杂志,2017,19(12):1297-1300,4.

基金项目

国家重点基础研究发展计划(973 计划)(2013CB945401). (973 计划)

中国当代儿科杂志

OA北大核心CSCDCSTPCD

1008-8830

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