中国现代手术学杂志2017，Vol.21Issue(5)：357-360,4.DOI:10.16260/j.cnki.1009-2188.2017.05.009
婴幼儿主动脉缩窄合并心内畸形及肺动脉高压的外科治疗
Single-stage Correction of Coarctation of Aorta with Intracardiac Anomalies and Pulmonary Arterial Hypertension in Infants
摘要
Abstract
Objective To explore the clinical experiences of surgical treatments for coarctation of aorta (COA)with intracardiac anomalies and pulmonary arterial hypertension (PAH)in infants. Methods A retro-spective case-control study was carried out in 36 infants operated in our hospital during February 2012 to February 2017. There were 16 cases with COA and PAH in group A,and 20 cases with ventricular septal defect(VSD)and PAH in group B. The perioperative clinical data and follow-up data of the two groups were compared. Results All the patients were operated by both arch repair and intracardiac anomalies repair completed via sternotomy un-der extracorporeal circulation in single-stage. There was no significant difference of the mean pulmonary arterial pressure preoperatively between the two groups(P>0. 05). By the end of extracorporeal circulation,the mean pulmonary arterial pressure of group A was (28. 4 ± 8. 8)mmHg(1mmHg=0. 133 kPa),which was higher than (21. 2 ± 5. 0 )mmHg of group B(P<0. 05). It was longer in extracorporeal circulation time,aortic block time and postoperative ventilator aeration time of group A(P<0. 05). There was no mortality,nor paraplegia after operation. The postoperative arterial pressure gradient between the upper and the lower extremities was less than 10 mmHg,and no PAH was found under ultrasound detection 3 months after operation. Conclusions It would turn a rapider deteriorate in infants of COA and left to right shunt combined with PAH. It may get satis-factory effect if correction of the heart malformation and relief of COA could achieve in time.关键词
主动脉缩窄/肺动脉高压/体外循环Key words
aortic coarctation/pulmonary arterial hypertension/extracorporeal circulation分类
医药卫生引用本文复制引用
周文武,伍明,陈飞,侯安新,周庆,张志功,杨劲松..婴幼儿主动脉缩窄合并心内畸形及肺动脉高压的外科治疗[J].中国现代手术学杂志,2017,21(5):357-360,4.基金项目
湖南省卫生和计划生育委员会湖南省高层次人才"225"工程项目(编号:225人才计划2013-13) （编号:225人才计划2013-13）
