浙江医学2017，Vol.39Issue(19)：1664-1666,后插3,4.DOI:10.12056/j.issn.1006-2785.2017.39.19.2017-1253
肿瘤大小分类对0～Ⅲ期结直肠癌预后的影响
Correlation of tumor size classification with TNM classification and prognosis of colorectal cancer
摘要
Abstract
Objective To investigate the correlation of tumor size classifications with TNM classification and prognosis of colorectal cancer.Methods Clinical data 538 patients with colorectal cancer,who were surgically treated from January 2006 to January 2010 and followed for 5 years,were retrospectively reviewed.The tumor grades were classified by three tumor size classifications:classification A (≤ 1,＞ 1 ～ ≤ 3,＞ 3～ ≤ 5,＞ 5),classification B (≤ 2,＞ 2～ ≤ 5,＞ 5),classification C (≤ 2,＞ 2～ ≤ 4,＞4).The correlation of three tumor size classifications with TNM 6th combined sub-staging was analyzed with CROSS TAB and exact x2 test.Kaplan-Meier method was used for survival analysis,the multivariate COX regression was applied to analyze the independent factors for prognosis.Results Three tumor size classifications were positively correlated with TNM stages (rs=0.436,0.379 and 0.415,all P＜0.01).There were significant differences in 5-year overall survival rate among different grades in all three classifications (all P＜0.01).Multivariate Cox regression showed that the risk coefficients of three classifications were (0.401,95％ CI:0.025-6.412,P=0.006),(4.586,95％ CI:0.523-40.181,P=0.169) and (1.121,95％ CI:0.816-1.541,P=0.48).Conclusion Three tumor size classifications are correlated to TNM stage and prognosis of colorectal cancer,while only classification A is an independent determinant factor for prognosis of patient.关键词
结直肠癌/TNM分期/预后Key words
CRC/TNM stage/Prognosis引用本文复制引用
童国俊,钮萍萍,严强,张贵阳,刘剑,郑照正,陈燕,祁飞,余胜,徐旭婷..肿瘤大小分类对0～Ⅲ期结直肠癌预后的影响[J].浙江医学,2017,39(19):1664-1666,后插3,4.基金项目
浙江省科技计划项目(2017C33189) （2017C33189）
