浙江医学2017，Vol.39Issue(19)：1667-1670,4.DOI:10.12056/j.issn.1006-2785.2017.39.19.2017-1043
桐庐县居民高尿酸血症流行病学调查及其与慢性肾脏病的关系研究
Epidemiological features of hyperuricemia in Tonglu county and its relationship with chronic renal disease
摘要
Abstract
Objective To analyze the epidemiological features of hyperuricemia (HUA) in Tonglu county and its relationship with chronic kidney disease (CKD).Methods A total of 55,456 local residents aged 10-97 years underwent health check-up in Tonglu county First People's Hospital from 2011 to 2016.The prevalence of HUA and CKD,the risk factors of CKD and the progression of CKD in residents with HUA were analyzed.Results The prevalence of HUA in Tonglu county was increasing from 2011 to 2015,and the prevalence of CKD was relatively stable.The average prevalence of HUA was 27.55％,and the prevalence of males was higher than that of females (38.20％ vs 12.79％,P＜0.05).The average prevalence of CKD was 8.77％,and the prevalence of males was also higher than that of females (10.91％ vs 5.81％,P＜0.05).The average prevalence of HUA and CKD in male residents over 60 years was higher than that in female (P＜0.05).Male sex,age,higher uric acid,LDL-C,urea nitrogen levels were risk factors of CKD,while female sex,higher albumin,HDL-C,fasting blood glucose,hemoglobin levels were protective factors of CKD.The progression of CKD in HUA patients were significantly faster than those of non-HUA patients (P＜0.05).Conclusion The epidemiological characteristics of HUA in Tonglu county are similar to those in other regions of China.The progression of CKD in HUA patients is faster than that of non-HUA patients.关键词
高尿酸血症/慢性肾脏病/流行病学Key words
Hyperuricemia/Chronic kidney disease/Epidemiology引用本文复制引用
余戈平,周芳芳,徐晓,邢小中,欧阳玉萍,王芝芩,刘燕,王伟铭..桐庐县居民高尿酸血症流行病学调查及其与慢性肾脏病的关系研究[J].浙江医学,2017,39(19):1667-1670,4.基金项目
杭州市卫生科技计划项目(2015B42) （2015B42）
