川北医学院学报2017，Vol.32Issue(5)：684-687,4.DOI:10.3969/j.issn.1005-3697.2017.05.010
CT引导下肺穿刺活检诊断肺部局灶性磨玻璃密度结节失败因素分析
Failure factor analysis of CT guided PTNB for fGGN in diagnosis
摘要
Abstract
Objective:To evaluate the diagnosis failure,complications and influencing factors of CT-guided percutaneous lung biopsy (PTNB) for focal ground-glass nodule (fGGN) in the lung.Methods:80 subjects with fGGN were retrospectively investigated for diagnosis failure cases(defined as nondiagnostic,false positive,and false negative results),complications and influencing factors.Results:There were 9 false negative results identified as diagnostic failure cases,with 12 subjects each had a pneumothorax,and mild bleeding occurred in 16 subjects.Multivariate logistic regression analysis revealed that lesion size ≤ 10 mm,GGO percentage ＞ 90％ and needle distance ＞ 9 cm were significant independent risk factors for failure diagnosis.Lesion size ≤ 10 mm,lesions in the lower lobe,GGO percentage ＞ 90％,needle distance ＞ 9 cm,pleural passages ＞ 2 times and emphysema along the needle pathway were significant independent risk factors for emphysema pneumothorax.Lesion size ≤ 10 mm,lesions in the lower lobe,GGO percentage ＞ 90％,and needle distance ＞ 9 cm were significant independent risk factors for hemorrhage.Conclusion:CT-guided PTNB can be used as an important clinical diagnostic method for fGGN,but it should be alert to diagnosis failure,complications and its influencing factors.关键词
肺/活组织检查/局灶性磨玻璃密度结节/体层摄影术/X线计算机Key words
Lung/Biopsy/Ground-glass nodule/Tomography/X-ray computed分类
医药卫生引用本文复制引用
严高武,杨汉丰,杜勇,杨国庆,付泉水,陈洪,曾浩,范晓萍,胡纳,沈小程,徐晓雪..CT引导下肺穿刺活检诊断肺部局灶性磨玻璃密度结节失败因素分析[J].川北医学院学报,2017,32(5):684-687,4.基金项目
国家自然科学基金(81141067) （81141067）
遂宁市中心医院科研项目(2016S05) （2016S05）
