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基于介电特性的人体恶性胃组织支持向量机辅助诊断方法

张洒 厉周 辛学刚

南方医科大学学报2017,Vol.37Issue(12):1637-1642,6.
南方医科大学学报2017,Vol.37Issue(12):1637-1642,6.DOI:10.3969/j.issn.1673-4254.2017.12.13

基于介电特性的人体恶性胃组织支持向量机辅助诊断方法

Support vector machine-assisted diagnosis of human malignant gastric tissues based on dielectric properties

张洒 1厉周 2辛学刚1

作者信息

  • 1. 南方医科大学生物医学工程学院,广东 广州510515
  • 2. 南方医科大学珠江医院普外科,广东 广州510280
  • 折叠

摘要

Abstract

Objective To achieve differential diagnosis of normal and malignant gastric tissues based on discrepancies in their dielectric properties using support vector machine.Methods The dielectric properties of normal and malignant gastric tissues at the frequency ranging from 42.58 to 500 MHz were measured by coaxial probe method,and the Cole-Cole model was used to fit the measured data. Receiver-operating characteristic (ROC) curve analysis was used to evaluate the discrimination capability with respect to permittivity, conductivity, and Cole-Cole fitting parameters. Support vector machine was used for discriminating normal and malignant gastric tissues, and the discrimination accuracy was calculated using k-fold cross-validation.Results The area under the ROC curve was above 0.8 for permittivity at the 5 frequencies at the lower end of the measured frequency range.The combination of the support vector machine with the permittivity at all these 5 frequencies combined achieved the highest discrimination accuracy of 84.38% with a MATLAB runtime of 3.40 s.Conclusion The support vector machine-assisted diagnosis is feasible for human malignant gastric tissues based on the dielectric properties.

关键词

介电特性/恶性胃组织/鉴别/ROC曲线/支持向量机

Key words

dielectric properties/malignant gastric tissues/discrimination/support vector machine

引用本文复制引用

张洒,厉周,辛学刚..基于介电特性的人体恶性胃组织支持向量机辅助诊断方法[J].南方医科大学学报,2017,37(12):1637-1642,6.

基金项目

(201704020091))广州市产学研协同创新重大专项(201704020091)Supported by National Key Research and Development Program of China(2016YFC0100800,2016YFC0100801) (201704020091)

Supported by National Natural Science Foundation of China(61528102,61671229) (61528102,61671229)

南方医科大学学报

OA北大核心CSCDCSTPCDMEDLINE

1673-4254

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