国际口腔医学杂志2018，Vol.45Issue(1)：55-58,4.DOI:10.7518/gjkq.2018.01.011
牙龈干细胞生物学潜能的研究进展
A review on recent developments in pluripotency of gingiva-derived mesenchymal stem cells
摘要
Abstract
Mesenchymal stem cells (MSCs) which can be isolated from multiple tissue, have two specific characteristics: self-renewal and multi- or pluripotency. Recent evidence has shown that MSCs also located in gingiva, then be named as gingiva-derived mesenchymal stem cells (GMSCs). GMSCs represent a unique population of MSCs that can be easily isolated and obtained. In addition to maintaining a normal karyotype and telomerase activity in long-term cultures, GMSCs can display a stable phenotype and rapidly proliferatein vitro. Therefore, GMSCs are increasingly become the sources of stem cells for tissue engineering and regenerative medicine research. This review described the research progress of GMSCs' separation and identification, biological characteristics and differentiation ability and so on.关键词
间充质干细胞/牙龈干细胞/分化/组织再生Key words
mesenchymal stem cells/gingiva-derived mesenchymal stem cells/differentiation/tissue regeneration分类
生物科学引用本文复制引用
刘珍珍,方蛟,赵静辉,邹净亭,相星辰,王佳,周延民..牙龈干细胞生物学潜能的研究进展[J].国际口腔医学杂志,2018,45(1):55-58,4.基金项目
高等学校博士学科点专项科研基金(20120061110077) （20120061110077）
国家自然科学基金(81200809) （81200809）
吉林省教育厅"十二五"科学技术研究项目(吉教科合字[2015]第532号) （吉教科合字[2015]第532号）
吉林大学研究生创新基金资助项目(2017014,2017063) This study was supported by Specialized Research Fund for the Doctoral Program of Higher Education of China (20120061110077), National Natural Science Foundation of China (81200809), Science and Technology Research Project of Jilin Provincial Education Department in 12th Five-Year ([2015]532) and Project Supported by Graduate Innovation Fund of Jilin University (2017014, 2017063). （2017014,2017063）
