海南医学院学报2017,Vol.23Issue(20):2772-2775,4.DOI:10.13210/j.cnki.jhmu.20171009.007
循环运动训练联合药物治疗对T2DM患者糖脂代谢、微炎症状态的影响
Effect of circuit exercise training combined with drug therapy on glucose lipid metabolism and microinflammatory state in T2DM patients
摘要
Abstract
Objective:To study the effect of circuit exercise training combined with drug therapy on glucose lipid metab-olism and microinflammatory state in T2DM patients.Methods:Patients with newly diagnosed T2DM who were treated in Dazhou Integrated Traditional Chinese and Western Medicine Hospital between June 2014 and October 2016 were selected and randomly divided into training intervention group and routine intervention group who received circuit exercise training interven-tion and routine exercise intervention respectively.The contents of glucose lipid metabolism indexes and inflammatory cytokines in serum as well as the contents of inflammatory cells in peripheral blood were determined before intervention and 8 weeks after intervention.Results:Serum FBG,F-Ins,HbA1c%,FFA,TC,LDL-C,ox-LDL,Chemerin,Resistin,IL-6,MCP-1 and CRP contents as well as peripheral blood CD14+CD16+cell contents of both groups of patients after intervention were lower than those before intervention while HDL-C,ADP and Vaspin contents were higher than those before intervention,and serum FBG,F-Ins,HbA1c%,FFA,TC,LDL-C,ox-LDL,Chemerin,Resistin,IL-6,MCP-1 and CRP contents as well as periph-eral blood CD14+CD16+cell content of training intervention group after intervention were lower than those of routine interven-tion group while HDL-C,ADP and Vaspin contents were higher than those of routine intervention group.Conclusion:Circuit exercise training for T2DM can be more effective in improving glucose lipid metabolism and inhibiting inflammatory response.关键词
2型糖尿病/循环运动训练/胰岛素抵抗/脂肪细胞因子/炎症反应Key words
type 2 diabetes mellitus/circuit exercise training/insulin resistance/adipocytokine/inflammatory re-sponse分类
医药卫生引用本文复制引用
汤晓莉,叶海媚,王小琴,代雷,刘润萍..循环运动训练联合药物治疗对T2DM患者糖脂代谢、微炎症状态的影响[J].海南医学院学报,2017,23(20):2772-2775,4.基金项目
达州市科技局课题项目(No.达(2014)116号)Project of Dazhou Municipal Science and Technology Bureau(No.Da(2014)116) (No.达(2014)