海南医学院学报2017，Vol.23Issue(22)：3066-3069,4.DOI:10.13210/j.cnki.jhmu.20171107.001
康复训练联合高压氧治疗对脑梗死患者康复期神经细胞因子分泌及氧化应激反应的影响
Effect of rehabilitation training combined with hyperbaric oxygen therapy on the nerve cyto-kine secretion and oxidative stress in rehabilitation period of patients with cerebral infarction
摘要
Abstract
Objective:To discuss the influence of rehabilitation training combined with hyperbaric oxygen therapy on the nerve cytokine secretion and oxidative stress in rehabilitation period of patients with cerebral infarction.Methods:A total of 11O patients with cerebral infarction who received rehabilitation therapy in the hospital between January 2O15 and May 2O17 were divided into routine group(n=55)and hyperbaric oxygen group(n=55)according to random number table.Routine group re-ceived regular rehabilitation training,and hyperbaric oxygen group underwent rehabilitation training combined with hyperbaric oxygen therapy.The differences in the serum contents of nerve factors,neurotransmitters and oxidative stress indexes were compared between the two groups at immediately after admission(TO)and after 14d of treatment(T1).Results:At TO,there was no statistically significant difference in the serum contents of nerve factors,neurotransmitters and oxidative stress indexes between the two groups.At T1,serum nerve factors MBP and NSE contents of hyperbaric oxygen group were lower than those of routine group while NGF content was higher than that of routine group;serum neurotransmitter Glu content was lower than that of routine group while GABA content was higher than that of routine group;serum oxidative stress indexes ROS and LHP contents were lower than those of routine group while CAT and SOD contents were higher than those of routine group.Conclu-sions:Rehabilitation training combined with hyperbaric oxygen therapy can effectively optimize the nerve function and inhibit the systemic oxidative stress response in rehabilitation period of patients with cerebral infarction.关键词
脑梗死/康复训练/高压氧/神经细胞因子/氧化应激Key words
Cerebral infarction/Rehabilitation training/Hyperbaric oxygen/Nerve cytokine/Oxidative stress分类
医药卫生引用本文复制引用
孔铃,张玮,赵森..康复训练联合高压氧治疗对脑梗死患者康复期神经细胞因子分泌及氧化应激反应的影响[J].海南医学院学报,2017,23(22):3066-3069,4.基金项目
潜江市科技局一般项目(16cd0816) It is supported by General Project of Science and Technology Bureau(16cd0816). （16cd0816）
