海南医学院学报2017，Vol.23Issue(22)：3176-3179,4.DOI:10.13210/j.cnki.jhmu.20171012.006
依托咪酯复合丙泊酚方案对无痛胃肠镜检查过程中应激及炎症反应的影响
Effectof etomidate combined with propofol on stress and inflammatory response in painless gastrointestinal endoscopy
摘要
Abstract
Objective:To study the effect of etomidate combined with propofol on stress and inflammatory response in painless gastrointestinal endoscopy.Methods:38O subjects who received painless gastrointestinal endoscopy in the hospital were selected as the research subjects and divided into control group and observation group by random number table,19O cases in each group.Control group received propofol intravenous anesthesia,and observation group received etomidate combined with propofol intravenous anesthesia.The differences in serum levels of stress indexes and inflammatory factors were compared be-tween the two groups 24h before examination,during examination and 1h after examination.Results:24h before examination, difference in serum levels of stress indexes and inflammatory factors were not statistically significant between the two groups of subjects(P>O.O5).During examination and 1h after examination,serum NE,E,Cor,ALD,AT-Ⅱ,IL-1β,IL-4,IL-6,IL-8,IL-1O and TNF-α contents of both groups were higher than those 24h before examination(P<O.O5),and serum NE,E, Cor,ALD,AT-Ⅱ,IL-1β,IL-4,IL-6,IL-8,IL-1O and TNF-α contents of observation group were lower than those of control group(P<O.O5).Conclusion:Etomidate combined with propofol for painless gastrointestinal endoscopy can effectively allevi-ate the stress and inflammatory response during and early after the examination.关键词
无痛胃肠镜/依托咪酯/丙泊酚/应激反应/炎症反应Key words
Painless gastrointestinal endoscopy/etomidate/propofol/stress response/inflammatory response分类
医药卫生引用本文复制引用
谢东武..依托咪酯复合丙泊酚方案对无痛胃肠镜检查过程中应激及炎症反应的影响[J].海南医学院学报,2017,23(22):3176-3179,4.基金项目
绵阳市卫生局科研基金资助项目(201119) Project of research fund of Mianyang Municipal Health Bureau(201119) （201119）
