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Onyx胶介入栓塞法与伽玛力治疗颅内动静脉畸形对照研究

曾庆 周国平 曾宪强 赵晓阳 李杨

中国实用神经疾病杂志2017,Vol.20Issue(23):75-79,5.
中国实用神经疾病杂志2017,Vol.20Issue(23):75-79,5.DOI:10.3969/j.issn.1673-5110.2017.23.019

Onyx胶介入栓塞法与伽玛力治疗颅内动静脉畸形对照研究

Comparative study of Onyx glue embolization method and Gamma knife for arterovenous malformations

曾庆 1周国平 2曾宪强 1赵晓阳 3李杨4

作者信息

  • 1. 郑州大学附属南阳医院介入科,河南南阳473000
  • 2. 郑州大学附属南阳医院神经外科,河南南阳473000
  • 3. 河南省人民医院介入科,河南郑州450003
  • 4. 南阳医学高等专科学校医学技术系,河南南阳473000
  • 折叠

摘要

Abstract

Objective To investigate the clinical effect of Onyx glue embolization in the treatment of arterovenous malfor-mations (AVM ) and its postoperative follow-up study in near and medium term .Methods From April 2014 to June 2016 ,selected 69 patients with AVM in our hospital were randomly divided into control group (n=34) and observation group (n=35) ,the con-trol group was treated with Gamma knife ,and the observation group was treated with Onyx adhesion embolization .Lesion treat-ment ,lesion size reduction ,hospital stay ,and improved Rankin score were observed and compared between the two groups .The in-cidence of complications and the quality of life (QOL) score were statistically analyzed .Results The total embolization rate was 65.71% (23/35) in the observation group ,which was higher than that in the control group (26.47% ,9/34) ,the difference was statistically significant (P<0.05) .The size of the lesion in the observation group was larger than that in the control group ,the difference was statistically significant (P<0.05) .The corrected Rankin score of the observation group was lower than that of the control group at 3 months and 1 year after operation ,the difference was statistically significant (P<0.05) .The incidence of com-plications in the observation group was 5.71% (2/35) ,which was lower than that in the control group (26.47% ,9/34) ,the differ-ence was statistically significant (P<0.05) .The QOL score of the observation group was higher than that of the control group at 3 months after operation ,the difference was statistically significant (P<0.05) .Conclusion Onyx adiplectic embolization can im-prove the neurological function ,reduce the lesion volume ,improve the quality of life in AVM patients with higher embolization rate and the lower incidence of complication .

关键词

颅内动静脉畸形/Onyx胶介入栓塞法/伽玛刀/预后/神经介入/中青年

Key words

Arterovenous malformations/Onyx glue interventional embolization/Gamma knife/Prognosis/Neurological in-tervention/Young and middle-aged

分类

医药卫生

引用本文复制引用

曾庆,周国平,曾宪强,赵晓阳,李杨..Onyx胶介入栓塞法与伽玛力治疗颅内动静脉畸形对照研究[J].中国实用神经疾病杂志,2017,20(23):75-79,5.

基金项目

中国脑卒中高危人群干预适宜技术研究及推广项目(编号:GN-2016R0004) (编号:GN-2016R0004)

中国实用神经疾病杂志

1673-5110

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