中国实用神经疾病杂志2017，Vol.20Issue(24)：18-20,3.DOI:10.3969/j.issn.1673-5110.2017.24.004
颅脑损伤后血浆血管紧张素水平与脑血管痉挛发生的相关性研究
A research of relevance between angiotensin in plasma and cerebral vasospasm after traumatic brain injury
摘要
Abstract
Objective To investigate the relevance between angiotensin in plasma and cerebral vasospasm after traumatic brain injury .Methods 238 patients with traumatic craniocerebral injury treated from January 2015 to January 2015 were collected , and tested plasma angiotensin on 1st ,3th ,7th ,14th ,21th ,28th days ,at the same time the velocity of intracranial vascular blood flow were examined by the application of transcranial doppler ultrasound to reflect cerebral vasospasm .The relationship between the angiotensin and cerebral vasospasm were compared .Results There was a positively correlation between the cerebral blood flow velocity and plasma angiotensin concentrations of 238 patients ,and the correlation coefficients were 0.58 ,0.72 ,0.66 ,0.51 ;After craniocerebral injury plasma angiotensin began to rise rapidly ,peaked on 7th day ,and then slowly declined .Cerebral blood flow velocity in patients after craniocerebral injury has been rising ,peaked on 7th day ,and then slowly declined .Conclusion After traumatic craniocerebral injury there is significant correlation between cerebral vasospasm and plasma angiotensin .Plasma angio-tensin plays an important role in the process of cerebral vasospasm after traumatic craniocerebral injury .关键词
颅脑损伤/血管紧张素/脑血管痉挛/经颅多普勒超声/脑脊液Key words
Traumatic brain injury/Angiotensin/Cerebral vasospasm/Transcranial doppler ultrasonography/Cerebrospinal fluid分类
医药卫生引用本文复制引用
吴恒浩,申娟茹,郑光明,张万宏,孙建中..颅脑损伤后血浆血管紧张素水平与脑血管痉挛发生的相关性研究[J].中国实用神经疾病杂志,2017,20(24):18-20,3.基金项目
开封市科技发展计划项目 ,编号:1403061 （）
