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运动训练对帕金森病非运动症状的改善作用研究

刘利 谢雯 陈丽 刘江静 杨春娟 赵光辉

中国实用神经疾病杂志2017,Vol.20Issue(24):40-43,4.
中国实用神经疾病杂志2017,Vol.20Issue(24):40-43,4.DOI:10.3969/j.issn.1673-5110.2017.24.009

运动训练对帕金森病非运动症状的改善作用研究

Study on the improvement of physical training on the non-motor symptoms of Parkinson's disease

刘利 1谢雯 2陈丽 2刘江静 3杨春娟 3赵光辉4

作者信息

  • 1. 西安交通大学第一附属医院急诊科,陕西西安710061
  • 2. 西安交通大学医学部基础医学院,陕西西安710061
  • 3. 陕西省康复医院神经内科,陕西西安710061
  • 4. 西安交通大学附属红会医院,陕西西安710054
  • 折叠

摘要

Abstract

Objective To investigate the effect of physical training on the non-motor symptoms of Parkinson's disease pa-tients .Methods Using the method of retrospective analysis and follow-up ,305 cases of Parkinson's disease (PD) diagnosed in Shaanxi Province Rehabilitation Hospital from March 2012 to September 2014 were investigated by Hamilton depression scale (HAMD scale 17) ,Hamilton anxiety scale (HAMA scale) and Alzheimer's disease assessment scale (ADAS-cog) evaluation .To-tally 239 patients who meet the requirements were divided into three groups :A depression group ,B anxiety group and C cognitive impairment group (when the patient had more than two kinds of symptoms meantime ,grouping according to the highest score) , then the exercise attitude with'exercise attitude scale',correlation analysis between non motor symptoms and each factor were in-vestigated .Executing the'physical training program'for 3—6 months to patients with factor's score was lower than normal ,then factor scores with exercise attitude scale ,HAMD ,HAMA and ADAS-cog scores were investigated again .Results There was a sig-nificant negative correlation between physical attitude and non motor symptoms in PD patients with mental and cognitive impair-ment and the physical attitude lower than normal (r<0 ,P<0.05) .After physical training ,the patients'emotional and cognitive impairment scores were significantly reduced(P<0.05) .Conclusion Continuous physical training can effectively improve the ex-ercise attitude of patients with PD ,and improve the non-symptoms .

关键词

帕金森病/抑郁/焦虑/认知障碍/运动训练

Key words

Parkinson's disease/Depression/Anxiety/Cognitive impairment/Exercise attitud

分类

医药卫生

引用本文复制引用

刘利,谢雯,陈丽,刘江静,杨春娟,赵光辉..运动训练对帕金森病非运动症状的改善作用研究[J].中国实用神经疾病杂志,2017,20(24):40-43,4.

基金项目

陕西省自然科学基金面上项目(2016JM8011) (2016JM8011)

西安交通大学基本科研业务费(xjj2015080 ) (xjj2015080 )

西安市科技计划项目(2017118SF/YX012(6)) (2017118SF/YX012(6)

中国实用神经疾病杂志

1673-5110

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