中医药导报2017,Vol.23Issue(23):57-62,6.
穴位贴敷治疗支气管哮喘临床疗效的Meta分析
Meta-Analysis and Evaluation on the Clinical Efficacy of Bronchial Asthma with Acupoint Application
摘要
Abstract
Objective:To systematically evaluate the Clinical effects and safety of acupoint application in the treatment of bronchial asthma.Methods:We explored literature from the Pubmed,CBM,CNKI,VIP,WANFANG DATA from build library time until July 2016,to put the clinical effect,pulmonary function test (PFT),score of asthma control test (ACT),score of TCM symptom and adverse reaction as the effective index.Then,meta-analysis was performed using RevMan 5.3 software.Results:A total of 14 RCTs involving 1,953 participants were included.The results of rcta-analysis showed that the total clinical effective rate in the acupoint application group was higher than that of control group [RR=1.20,95%CI (1.14,1.27).Improvement of PFT was significantly better than that of control group [The change of FEV1% was significantly lower than those in control group [WMD=7.82,95% CI (6.64,8.99)].The change of PEF value was significantly higher than that of control group [SMD=0.72,95%CI(0.50,0.94)];The change of FEV1/FVC% was significantly higher than that of control group [SMD=0.57,95%CI (0.21,0.94)].Scores of ACT were significantly higher than those in control group.There was profoundly significant difference in ACT between two groups [WMD=1.31,95%CI (0.82,1.80)].At the same time,the adverse reaction of the therapy of acupoint application is little.Conclusion:Acupoint application can effectively alleviate the clinical symptoms of bronchial asthma patients,improve the patient's PFT,and increase the quality of life.However,due to the limitation of the quality and quantity of included studies,the above conclusion needs to be further verified by more large samples,multi center and high quality studies.关键词
支气管哮喘/穴位贴敷/随机对照试验/系统评价/Meta分析Key words
bronchial asthma/acupoint application/systematic evaluatio/RCT/meta-analysisn分类
医药卫生引用本文复制引用
翟亚玲,曲妮妮,石晓乐,刘勇明,房繄恭..穴位贴敷治疗支气管哮喘临床疗效的Meta分析[J].中医药导报,2017,23(23):57-62,6.基金项目
“十二五”国家科技支撑计划(2015BAI04Bl1),项目名称:冬病夏治穴位贴敷预防支气管哮喘发作的临床评价及技术操作规范研究 (2015BAI04Bl1)