中医药导报2017，Vol.23Issue(23)：63-67,5.
丹栀逍遥散加减治疗2型糖尿病合并抑郁症的Meta分析
Danzhi Xiaoyao Powder（丹栀逍遥散） Adjustment on the Treatment of Type 2 Diabetes Mellitus Complicating Depression: A Meta-Analysis
摘要
Abstract
Objective:To evaluate the clinical effect of Danzhi Xiaoyao powder adjustment on the treatment of type 2 diabetes mellitus complicating depression.Methods:We summarized journals related literature up to April 8th,2016,according to computer search and artificial methods,to search study papers of randomized control trials of Danzhi Xiaoyao powder adjustment on the treatment of type 2 diabetes mellitus complicating depression.Bias risk evaluation tool offered by Cochrane collaboration was applied to do methodo-logieal quality assessment on included studies.Meta-analysis of FBG,2h PBG,HbA1c,HAMD,SDS was applied by software Revman 5.1.Results:A Total of seven studies were included,involving 490 patients.There was high risk of bias.Meta analysis results showed that compared with the control group,Danzhi Xiaoyao powder adjustment can reduce the FBG [MD=-1.04,95％CI (-1.65,-0.43),P=0.000,9],2h PBG [MD=-1.45,95％CI (-1.66,-1.25),P＜0.000,01],HbA1c[MD=-1.00,95％CI (-1.48,-0.52),P＜0.00,01],HAMD [MD=-3.59,95％CI (-6.33,-0.85),P=0.01],SDS [MD=-8.61,95％C1 (-9.53,-7.69),P＜0.000,01].Conclusion:Danzhi Xiaoyao powder adjustment can decrease FBG,2h PBG,HAMD,SDS in patients of type 2 diabetes mellitus complicating depression.But definite conclusion remains to be examined by more high-quality studies.关键词
丹栀逍遥散/糖尿病/抑郁症/Meta分析Key words
Danzhi Xiaoyao powder adjustment/type 2 diabetes mellitus/depression/Meta analysis分类
医药卫生引用本文复制引用
张韦华,程红卫,冯兴中..丹栀逍遥散加减治疗2型糖尿病合并抑郁症的Meta分析[J].中医药导报,2017,23(23):63-67,5.基金项目
国家中医药管理局“十二五”重点专科建设项目 （）
北京市中医管理局中西医结合神经内分泌免疫重点学科建设项目 （）
