检验医学与临床2017，Vol.14Issue(z2)：91-93,3.DOI:10.3969/j.issn.1672-9455.2017.26.036
探讨葡萄糖-6-磷酸脱氢酶缺乏对2型糖尿病患者血糖监测的影响
To investigate the effect of glucose 6 phosphate dehydrogenase deficiency on blood glucose monitoring in patients with type 2 diabetes mellitus
李美珠 1朱嫦琳 1郑明珠 1李炜煊1
作者信息
- 1. 广东省佛山市第一人民医院检验科 528000
- 折叠
摘要
Abstract
Objective To investigate the relationship between glucose 6 phosphate dehydrogenase (G6PD)deficiency with attac-king type 2 diabetes mellitus and the effect on the determination of glycosylated hemoglobin (HBA1C).Methods 131 cases pia-tients who were diagnosed type 2 diabetes mellitus divided into 2 groups 118 cases with diabetes and 13 cases with diabetes combi-ning with G6PD deficiency,55cases of healthy controls,2 cases of simple G6PD deficiency who is from 48 to 70 years old in our hos-pital from August 2015 to November 2015 were chosen as the control group.Detect and statistically analysis theirHBA1C level and froctoseamine level,G6PD,6-PGD activity and statistic their ratio.Results Compared with the control group,the diabetic group showed the same incidence of G6PD deficiency,the difference was not statistically significant (P>0.05).In the case of the type 2 diabetic group combining with G6PD deficiency,the HBA1C level was lower than that of type 2 diabetes mellitus,and the difference was statistically significant (P<0.05).Conclusion G6PD deficiency leads to low HBA1C level.At the same time,the detection of G6PD and HBA1C levels can better monitor and evaluate the blood glucose level of diabetic patients,which has clinical significance for the diagnosis and treatment of T2DM patients.关键词
葡萄糖-6-磷酸脱氢酶缺乏/糖化血红蛋/2型糖尿病Key words
G6PD deficiency/HBA1C/type 2 diabetes mellitus引用本文复制引用
李美珠,朱嫦琳,郑明珠,李炜煊..探讨葡萄糖-6-磷酸脱氢酶缺乏对2型糖尿病患者血糖监测的影响[J].检验医学与临床,2017,14(z2):91-93,3.
