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"太空人参酵母"对在模拟微重力下人原代成纤维细胞的保护作用

宋肖洁 史晓婷 吴越

日用化学工业2017,Vol.47Issue(12):698-702,5.
日用化学工业2017,Vol.47Issue(12):698-702,5.DOI:10.13218/j.cnki.csdc.2017.12.009

"太空人参酵母"对在模拟微重力下人原代成纤维细胞的保护作用

Protective effect of"space ginseng yeast"on human primary fibroblasts under microgravity condition

宋肖洁 1史晓婷 1吴越1

作者信息

  • 1. 伽蓝(集团)股份有限公司研发中心,上海 200233
  • 折叠

摘要

Abstract

Through the multi -index parameters,a variety of experiments have been designed to verify the protection effects of"space ginseng yeast"on human primary fibroblasts. Results show that"space ginseng yeast"can improve the cell morphology and survival rate in the human primary fibroblasts induced by microgravity;restore the expression and arrangement of cytoskeletal protein like Tubulin,and extracellular matrix protein like Integrin and Fibronectin;as well as inhibit the abnormal expression of MMP-1 . The protective effect of"space ginseng yeast",which is diluted by 20 to 500 times,is better,and the protective effect of 100 times diluted"space ginseng yeast"shows the most obvious result.

关键词

抗衰老化妆品/太空人参酵母/模拟微重力/人原代成纤维细胞/细胞骨架蛋白

Key words

anti-aging cosmetics/"space ginseng yeast"/simulated microgravity/human primary fibroblasts/cytoskeletal protein

分类

化学化工

引用本文复制引用

宋肖洁,史晓婷,吴越.."太空人参酵母"对在模拟微重力下人原代成纤维细胞的保护作用[J].日用化学工业,2017,47(12):698-702,5.

日用化学工业

OA北大核心CSCDCSTPCD

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