生物医学工程研究2017，Vol.36Issue(4)：287-290,4.DOI:10.19529/j.cnki.1672-6278.2017.04.02
基于脉搏色素光密度法的心输出量测量系统
Cardiac Output Measurement System based on Pulse Dye Densitometry
摘要
Abstract
Cardiac output (CO) and other cardiovascular hemodynamic parameters were taken as diagnostic basis of heart function condition and cardiovascular disease in clinic .But the traditional detection methods have disadvantages such as operation complex and surgical trauma , as well as possibility of complication for patients .To solve the problem , a cardiac output measurement system based on pulse dye densitometry ( PDD) was researched .With lambert beer 's law and dye dilution theory as the foundation , the noninvasive and real-time measurement of arterial indocyanine green ( ICG) dye concentration spectrum was realized , by choosing appropriate du-al wavelength detection light source (805nm and 940nm), and CO could be calculated from the concentration time curve of ICG .Com-pared with the "gold standard"method of thermodilution , the average relative error was 4.79% and the correlation coefficient was 0.99.The result indicates that the CO measurement system implements the noninvasive and accurate measurement and provides a new choice for clinical detection of CO .关键词
心输出量/脉博色素光密度法/吲哚氰绿/色素稀释理论/热稀释法Key words
Cardiac output/Pulse dye densitometry/Indocyanine green/Dye dilution theory/Thermodilution分类
医药卫生引用本文复制引用
赵银银,王钢,张大可,蔡靖..基于脉搏色素光密度法的心输出量测量系统[J].生物医学工程研究,2017,36(4):287-290,4.基金项目
国家"十二五"科技支撑计划(2015BAI02B04) （2015BAI02B04）
吉林省发改委省级产业创新专项资金项目(2016C052-2) （2016C052-2）
吉林省教育厅"十二五"科学技术研究规划重点项目(440020031134) （440020031134）
吉林省教育厅科学研究规划项目(JJKH20170034KJ,JJKH20170035KJ). （JJKH20170034KJ,JJKH20170035KJ）
