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半互穿网络淀粉基止血海绵的制备及性能研究

郈秀菊 朱爱臣 王军 孙淑娜 王晓晨 王传栋

生物医学工程研究2017,Vol.36Issue(4):370-374,5.
生物医学工程研究2017,Vol.36Issue(4):370-374,5.DOI:10.19529/j.cnki.1672-6278.2017.04.19

半互穿网络淀粉基止血海绵的制备及性能研究

The Preparation and Properties of Semi-interpenetrating Networks Starch Hemostatic Dressings

郈秀菊 1朱爱臣 1王军 2孙淑娜 2王晓晨 1王传栋1

作者信息

  • 1. 山东省药学科学院,山东省医用高分子材料重点实验室,济南 250101
  • 2. 山东省中医院,济南 250011
  • 折叠

摘要

Abstract

In this paper , the low temperature plasma technology and freeze drying technology was used to get the semi -interpene-trating networks starch hemostatic dressings .The experiment design scheme and preparation technology of the starch hemostatic dress -ings were optimized by the test results of the water absorption and expansion rate .The scanning electron microscopy images showed that the sponges prepared by this experiment had a uniform porous structure of the network skeleton .Rabbit liver and kidney bleeding ex-periments showed that the bleeding time was shorter and the blood loss was fewer by using the starch hemostatic dressings , and it was showed that the starch hemostatic dressings had good hemostatic effect .The results of the degradation in mice showed that the starch hemostatic dressings had been absorbed after four weeks .The semi-interpenetrating networks starch hemostatic dressing was a kind of rapid and effective absorbable hemostatic dressing .It has the very good application in the surgery .

关键词

淀粉/羟乙基纤维素/止血海绵/半互穿网络/生物降解

Key words

Starch/Hydroxyethyl cellulose/Hemostatic dressings/Semi-interpenetrating networks/Biodegradation

分类

医药卫生

引用本文复制引用

郈秀菊,朱爱臣,王军,孙淑娜,王晓晨,王传栋..半互穿网络淀粉基止血海绵的制备及性能研究[J].生物医学工程研究,2017,36(4):370-374,5.

基金项目

山东省糖产业省级重点实验室联盟资助项目(山东省科技厅2015年2060599科目). (山东省科技厅2015年2060599科目)

生物医学工程研究

OACSTPCD

1672-6278

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