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氧化应激与实热"上火"的相关性研究

李思敏 包洁 汪琴静 窦晓兵 范永升

世界中医药2017,Vol.12Issue(12):2872-2875,4.
世界中医药2017,Vol.12Issue(12):2872-2875,4.DOI:10.3969/j.issn.1673-7202.2017.12.002

氧化应激与实热"上火"的相关性研究

Study on Correlation between Oxidative Stress and Excess Heat"Shang huo"

李思敏 1包洁 2汪琴静 3窦晓兵 2范永升2

作者信息

  • 1. 浙江中医药大学附属第三医院,杭州,310005
  • 2. 浙江中医药大学,杭州,310053
  • 3. 浙江中医药大学附属江南医院,杭州,311201
  • 折叠

摘要

Abstract

Objective:To study the correlation between oxidative stress and excess heat "shanghuo" through observing the changes of blood lipid peroxidation index (MDA,ROS) and antioxidant indexes (GSH,T-AOC,SOD) in the population of excess heat"shanghuo".Methods:Excess heat "shanghuo" and normal population samples were collected,and the levels of MDA,GSH,SOD and T-AOC in plasma and ROS in peripheral blood leukocytes were detected and compared respectively.Results:The levels of MDA,GSH,SOD and T-AOC in the blood plasma of excess heat "shanghuo" were higher than those in the normal group (P<0.05),and the levels of ROS in leukocytes decreased significantly (P<0.01).Conclusion:The excess oxidation index (MDA) and antioxidant index (GSH,SOD,T-AOC) were all increased in excess heat "shanghuo" people,and the levels of ROS in leu-kocytes decreased significantly,indicating that excess heat "shanghuo" is closely related to oxidative stress;the organism is in a level state of oxidation and antioxidation,but the oxidation and antioxidant levels are in balance.

关键词

实热"上火"/氧化应激/MDA/ROS/GSH/T-AOC/SOD

Key words

Excess-heat "shanghuo"/Oxidative stress/MDA/GSH/T-AOC/SOD/ROS

分类

医药卫生

引用本文复制引用

李思敏,包洁,汪琴静,窦晓兵,范永升..氧化应激与实热"上火"的相关性研究[J].世界中医药,2017,12(12):2872-2875,4.

基金项目

国家重点基础研究发展计划(973计划)项目(2014CB543001) (973计划)

世界中医药

OACHSSCDCSTPCD

1673-7202

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