世界中医药2017,Vol.12Issue(12):2872-2875,4.DOI:10.3969/j.issn.1673-7202.2017.12.002
氧化应激与实热"上火"的相关性研究
Study on Correlation between Oxidative Stress and Excess Heat"Shang huo"
摘要
Abstract
Objective:To study the correlation between oxidative stress and excess heat "shanghuo" through observing the changes of blood lipid peroxidation index (MDA,ROS) and antioxidant indexes (GSH,T-AOC,SOD) in the population of excess heat"shanghuo".Methods:Excess heat "shanghuo" and normal population samples were collected,and the levels of MDA,GSH,SOD and T-AOC in plasma and ROS in peripheral blood leukocytes were detected and compared respectively.Results:The levels of MDA,GSH,SOD and T-AOC in the blood plasma of excess heat "shanghuo" were higher than those in the normal group (P<0.05),and the levels of ROS in leukocytes decreased significantly (P<0.01).Conclusion:The excess oxidation index (MDA) and antioxidant index (GSH,SOD,T-AOC) were all increased in excess heat "shanghuo" people,and the levels of ROS in leu-kocytes decreased significantly,indicating that excess heat "shanghuo" is closely related to oxidative stress;the organism is in a level state of oxidation and antioxidation,but the oxidation and antioxidant levels are in balance.关键词
实热"上火"/氧化应激/MDA/ROS/GSH/T-AOC/SODKey words
Excess-heat "shanghuo"/Oxidative stress/MDA/GSH/T-AOC/SOD/ROS分类
医药卫生引用本文复制引用
李思敏,包洁,汪琴静,窦晓兵,范永升..氧化应激与实热"上火"的相关性研究[J].世界中医药,2017,12(12):2872-2875,4.基金项目
国家重点基础研究发展计划(973计划)项目(2014CB543001) (973计划)