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甲状腺乳头状癌合并代谢综合征患者的复发特点

殷德涛 何华楠 马润声 李红强 王勇飞 江金花 王庆端

西安交通大学学报(医学版)2018,Vol.39Issue(1):17-21,5.
西安交通大学学报(医学版)2018,Vol.39Issue(1):17-21,5.DOI:10.7652/jdyxb201801005

甲状腺乳头状癌合并代谢综合征患者的复发特点

Characteristics of recurrent papillary thyroid cancer in metabolic syndrome patients

殷德涛 1何华楠 1马润声 1李红强 1王勇飞 1江金花 2王庆端2

作者信息

  • 1. 郑州大学第一附属医院甲状腺外科 ,河南省高等学校临床医学重点学科开放实验室 ,河南郑州 450052
  • 2. 河南省医药科学研究院 ,河南郑州 450052
  • 折叠

摘要

Abstract

Objective To explore the characteristics and components of recurrent papillary thyroid cancer in patients with metabolic syndrome .Methods We retrospectively reviewed the information of the patients with recurrent papillary thyroid cancer after initial surgery during January 1st ,2010 and December 31st ,2015 in the First Affiliated Hospital of Zhengzhou University .We compared tumor size ,lymph node metastasis ,recurrence time and postoperative invasion rate in metabolic syndrome and non-metabolic syndrome groups . Results Totally 82 patients were included with 34 men and 48 women .There was no significant difference between patients with and those without metabolic syndrome grouped by the classic diagnosis approach .However ,the lymph node metastasis grade of recurrent papillary thyroid cancer patients who also suffered from at least two metabolic disorders ,was lower ,especially in women (P=0 .002) .Moreover ,patients with metabolic disorders had shorter recurrence time (Pdiabetes=0 .034 , Pdyslipidemia =0 .037 , PBMI =0 .004 , PMetS2 =0 .036) .Conclusion Papillary thyroid cancer patients with metabolic disorder ,especially with two or more components of metabolic syndrome and overweight and/or obesity ,may have an increasing risk of recurrence .

关键词

代谢综合征/肥胖/甲状腺乳头状癌/复发/淋巴结转移

Key words

metabolic syndrome/obesity/papillary thyroid cancer/recurrence/lymphatic metastasis

分类

医药卫生

引用本文复制引用

殷德涛,何华楠,马润声,李红强,王勇飞,江金花,王庆端..甲状腺乳头状癌合并代谢综合征患者的复发特点[J].西安交通大学学报(医学版),2018,39(1):17-21,5.

基金项目

国家自然科学基金资助项目(No.81372863) (No.81372863)

河南省科技攻关项目(No.162102310514)Supported by the National Natural Science Foundation of China (No.81372863) and the Scientific and Technological Project of Henan Province (No.162102310514) (No.162102310514)

西安交通大学学报(医学版)

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