中国组织工程研究2017，Vol.21Issue(34)：5558-5564,7.DOI:10.3969/j.issn.2095-4344.2017.34.024
骨移植和组织工程支架材料在上颌窦提升口腔种植修复中的应用
Application of bone grafting and tissue engineering scaffold in oral implantation involving maxillary sinus elevation
摘要
Abstract
BACKGROUND: The persistence of bone atrophy and maxillary sinus gasification can cause a deficiency in the height of maxillary posterior teeth. It is very difficult to place dental implants at this site. Increasing bone mass in the maxilla is beneficial for dental implantation, and it is a currently accepted method to lift the maxillary sinus to compensate for bone loss. OBJECTIVE: To analyze the application effect of bone graft material, human working bone material and tissue engineering scaffold material in maxillary sinus elevation. METHODS: "Maxillary sinus elevation, dental implant, autologous bone, allograft, artificial bone, scaffold" were used as the key words in Chinese and English to retrieve relevant articles concerning materials used in maxillary sinus elevation included in PubMed and WanFang. Then, we analyzed the effects of different bone grafting materials on new bone formation, implant stability and bone-implant binding rate after maxillary sinus elevation. RESULTS AND CONCLUSION: Autologous bone is the gold standard of bone graft material in maxillary sinus elevation, which can ensure the bone mass and the long-term stability of implantation around the implant, but it is easy to cause secondary damage to the donor area and to produce infection. Allogeneic bone can be used as an alternative material of autogenous bone,such as deproteinized bovine bone minerals,inorganic bovine bone,etc.,which can generate new bone and ensure dental implantation to achieve sufficient stability. Artificial bone materials such as hydroxyapatite, beta-tricalcium phosphate,biphasic calcium phosphate compound,etc.have good bone conduction and can achieve a high bone-implant contact rate. Tissue-engineered bone grafts that can combine stem cells and cytokines with bio-scaffolds for maxillary sinus elevation can promote new bone formation, increase bone mass, and ensure dental implantation to achieve good stability.关键词
生物材料/植骨材料/同种异体骨/上颌窦提升/骨愈合/牙种植分类
医药卫生引用本文复制引用
李林峰,李月,李瑞玉,郝跃玲,李蒙,张俊会,党莹,李兵,王文杰..骨移植和组织工程支架材料在上颌窦提升口腔种植修复中的应用[J].中国组织工程研究,2017,21(34):5558-5564,7.基金项目
河北省中医药管理局资助项目(2014115)the Funded Project of Henan Provincial Administration of Traditional Chinese Medicine, No. 2014115 （2014115）
