中国组织工程研究2017，Vol.21Issue(35)：5577-5582,6.DOI:10.3969/j.issn.2095-4344.2017.35.001
膝单髁置换治疗晚期内侧间室膝关节自发性骨坏死
Unicompartmental knee arthroplasty used for advanced spontaneous osteonecrosis of the knee
摘要
Abstract
BACKGROUND: Unicompartment knee replacement is more popular for small trauma, rapid recovery, low less complications and almost normal knee mechanics, and has been used to repair unicompartmental knee diseases. At abroad, unicompartmental knee arthroplasty for advanced spontaneous osteonecrosis of knee (SONK) has obtained satisfactory outcomes, but its long-term efficacy and safety are not known in China. OBJECTIVE: To explore the short-term effectiveness of unicompartmental knee arthroplasty for advanced SONK. METHODS: Clinical data of 12 SONK patients (12 knees) admitted between January and August 2015 were analyzed retrospectively. Unicompartmental knee arthroplasty was operated by the same surgical team using the 3rdgeneration of Oxford?Unicompartmental Knee. The Visual Analogue Scale, femorotibial angle, range of motion of the knee and Hospital for Special Surgery scores were used to evaluate the curative efficacy at 3, 6, 12, and 18 months postoperatively. RESULTS AND CONCLUSION: (1) All patients were followed up for 12-18 months. The incision in all patients achieved primary union, and no infection, lower limb venous thrombosis or fracture occurred. (2) At the end of follow-up, the Visual Analogue Scale scores were significantly reduced from preoperative (6.67±0.78) to (1.75±0.97); the Hospital for Special Surgery scores were significantly increased from preoperative (63.92±7.27) to (91.67±2.87); the femorotibial angle changed from preoperative (178.28±3.38)° to (176.82±2.37)°(All P < 0.05). But the range of motion of the knee joint did not differ significantly before and after surgery. (3) That is to say, unicompartmental knee arthroplasty obtains satisfactory short-term efficacy in the treatment of advanced SONK.关键词
骨科植入物/人工假体/膝关节单髁置换术/膝关节自发性骨坏死/膝关节置换术/膝关节骨关节炎/骨坏死/膝关节退行性病变/膝关节疼痛/膝关节假体/国家自然科学基金分类
医药卫生引用本文复制引用
冯恩辉,麦秀钧,黄永明,曹振武,陈康耀,苏海涛..膝单髁置换治疗晚期内侧间室膝关节自发性骨坏死[J].中国组织工程研究,2017,21(35):5577-5582,6.基金项目
国家自然科学基金项目(81273781),课题名称:骨性关节炎中软骨细胞病变TDP-43负调控机制及补肾活血中药干预的研究the National Natural Science Foundation of China, No. 81273781 （81273781）
