全膝关节置换后假体周围感染病原菌分布特点及治疗策略
Periprosthetic joint infection following total knee arthroplasty: its bacteriological characteristics and treatment strategies
摘要
Abstract
BACKGROUND: Periprosthetic infection after total knee arthroplasty (TKA) has become the most serious complication. However, there is still a lack of clinical study on the distribution of pathogenic bacteria. Therefore, understanding the distribution characteristics of the main pathogenic bacteria is critical for preventing and treating OBJECTIVE: To analyze the bacteriological characteristics in the patients with periprosthetic joint infection following TKA, so as to provide reference for early prevention and treatment. METHODS: CNKI, VIP, WanFang and PubMed databases were retrieved for the literature concerning periprosthetic infection following TKA published before 2016. The incidence of periprosthetic joint infection after TKA was statistically analyzed. RESULTS AND CONCLUSION: (1) 103 articles were included, involving 1 399 patients. (2) The main pathogenic bacteria were Staphylococcus aureus,coagulase negative Staphylococcus aureus,Staphylococcus epidermidis,Escherichia coli, Streptococcus and Enterococcus.There is no significant difference in the distribution of bacteria at home and abroad. Treatment strategies are divided into conservative and surgical treatments. (3) The key for successfully preventing and treating periprosthetic infection after TKA lies in the multiple disciplinary team collaboration, understanding the distribution of bacteria, early diagnosis and active preventive measurements, as well as rational treatment strategies.关键词
骨科植入物/人工假体/全膝关节置换术/感染/细菌/病原菌/治疗/国家自然科学基金分类
医药卫生引用本文复制引用
崔苛苛,杨伟毅,刘军,潘建科,张葆青,曹学伟..全膝关节置换后假体周围感染病原菌分布特点及治疗策略[J].中国组织工程研究,2017,21(35):5721-5726,6.基金项目
国家自然科学基金项目(81473698) （81473698）
教育部高等学校博士点科研基金项目(20124425110004) （20124425110004）
广东省科技计划项目(2011B031700027) （2011B031700027）
广东省财政厅项目([2014]157号) （[2014]157号）
广东省中医药管理局项目(20164020) （20164020）
广东省中医院中医药科学技术研究专项(YK2013B2N19,YN2015MS15)the National Natural Science Foundation of China, No. 81473698 （YK2013B2N19,YN2015MS15）
the Doctoral Fund of Ministry of Education of China, No. 20124425110004 （）
the Science and Technology Program of Guangdong Province, No. 2011B031700027 （）
the Project of the Department of Finance of Guangdong Province, No. [2014]157 （）
the Project of Traditional Chinese Medicine Bureau of Guangdong Province, No. 20164020 （）
the Traditional Chinese Medicine Research Project of Guangdong Provincial Hospital of Chinese Medicine, No. YK2013B2N19 and YN2015MS15 （）
