西南国防医药2017，Vol.27Issue(12)：1310-1312,3.DOI:10.3969/j.issn.1004-0188.2017.12.021
原发性翼状胬肉与微血管密度的关系研究
Study on relation between primary pterygium and MVD
涂晶晶 1费秋香2
作者信息
- 1. 441000湖北襄阳,襄阳市襄州区人民医院眼科
- 2. 咸宁市中心医院湖北科技学院附属第一医院眼科
- 折叠
摘要
Abstract
Objective To explore the relation between primary pterygium and microvessel density (MVD).Methods Totally 481 patients with primary pterygium excise in our hospital were selected to constitute an observation group,with 481 specimens of pterygium taken;another 127 patients who had received strabotomy were selected to constitute a control group,with 127 bulbar conjunctiva specimens sampled.All specimens received routine histopathology and immunohistochemical staining examination.The MVD of the specimens and the positive rate of vascular endothelial growth factor (VEGF) between the two groups were compared and the relation between the MVD of pterygium and the positive rate of VEGF.Results The MVD of pterygium and the positive rate of VEGF in the observation group were much higher than those in the control group (P ＜ 0.05);the MVD of pterygium and the positive rate of VEGF in stationary phase were much lower than those in progressive phase (P ＜ 0.05);with the increase of the degree of infiltration of the limbus corneae by the pterygium,the positive rate of VEGF also increased progressively (P ＜ 0.05);Spearman correlation analysis showed that the MVD of pterygium were positively correlated with the positive rate of VEGF (r=0.504,P ＜ 0.05).Conclusion The MVD of pterygium and the positive rate of VEGF will increase with the pathological staging and clinical progress of pterygium;they can predict the progression of disease and are positively correlated with each other.关键词
翼状胬肉/角膜/微血管密度/浸润Key words
pterygium/cornea/MVD/infiltration分类
医药卫生引用本文复制引用
涂晶晶,费秋香..原发性翼状胬肉与微血管密度的关系研究[J].西南国防医药,2017,27(12):1310-1312,3.
