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非接触式光声成像技术及其应用

陈重江 周王婷 胡毅成 杨思华

中国医疗设备2018,Vol.33Issue(1):11-15,5.
中国医疗设备2018,Vol.33Issue(1):11-15,5.DOI:10.3969/j.issn.1674-1633.2018.01.003

非接触式光声成像技术及其应用

Noncontact Photoacoustic Imaging and Biomedical Application

陈重江 1周王婷 1胡毅成 1杨思华1

作者信息

  • 1. 华南师范大学生物光子学研究院 激光生命科学研究所、暨激光生命科学教育部重点实验室,广东 广州 510631
  • 折叠

摘要

Abstract

We reported a new photoacoustic signal detection method based on a low coherence Michelson interferometer, and established a noncontact photoacoustic imaging system. The feasibility of the method and imaging capability of the noncontact photoacoustic imaging system was testified by the mimic experiments. Experiment was conducted based on the noncontact photoacoustic imaging on the melanoma mouse ear in vivo.Results demonstrated that the noncontact photoacoustic imaging system could image the microvascular of biomedical tissues in vivo with high resolution. Compared with the traditional photoacoustic imaging system, which needs to be coupled to the imaging with coupling agent, this system has the advantage of non-contact detecting fashion, which avoids the contamination and maintenance of the coupling agent, thus it facilitates the practical application and extends the application of photoacoustic imaging in biomedicine.

关键词

光声成像/非接触式光声成像系统/生物医学应用/光学相干法

Key words

photoacoustic imaging/non-contact photoacoustic imaging system/biomedical application/optical interference method

分类

生物科学

引用本文复制引用

陈重江,周王婷,胡毅成,杨思华..非接触式光声成像技术及其应用[J].中国医疗设备,2018,33(1):11-15,5.

基金项目

国家自然科学基金(61705068 ()

61627827 ()

11774101 ()

81630046 ()

91539127) ()

广东省自然科学基金(2015B020233016 ()

2014B020215003 ()

2014A020215031 ()

2017A030310363) ()

广东省"特支计划"科技青年拔尖人才(2015TQ01X882) (2015TQ01X882)

广东省高等学校优秀青年教师培养计划(YQ2015049). (YQ2015049)

中国医疗设备

OACSTPCD

1674-1633

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