医药导报2018，Vol.37Issue(1)：1-5,5.DOI:10.3870/j.issn.1004-0781.2018.01.001
耐碳青霉烯类肠杆菌科细菌感染治疗策略研究进展
Treatment Strategies for Carbapenem-resistant Enterobacteriaceae Infections
摘要
Abstract
Objective Carbapenem-resistant Enterobacteriaceae infections is becoming a major challenge to clinicians, which resulted in extremely high mortality owing to the limited antibiotics option.It is urgently to explore strategies to manage such bacterial infections.So far,the research is mainly focused on the research and development of new drugs,as well as the re-evaluation of classic antimicrobial drugs and the combined treatment regimens.Tigecycline is available in our country,but the clinical effect is still doubtful.Polymyxin has a good effect on drug sensitivity test in vitro,but the clinical dosing has not been established.Carbapenems combining with other drugs as optimizing treatment program is also being explored.Carbapenemase-inhibitor combination has not yet listed on Chinese market.In the mean time,it is urgent to prevent and to control carbapenem-resistant Enterobacteriaceae bacterial infection.关键词
碳青霉烯类/耐药/肠杆菌科细菌/感染/治疗策略Key words
Carbapenem/Resistant/Enterobacteriaceae/Infection/Treatment strategies分类
医药卫生引用本文复制引用
肖婷婷,肖永红..耐碳青霉烯类肠杆菌科细菌感染治疗策略研究进展[J].医药导报,2018,37(1):1-5,5.基金项目
浙江省重大科技专项重大社会发展项目(2015C03032) （2015C03032）
