中国美容医学2017，Vol.26Issue(12)：87-90,4.
1550nm非剥脱性点阵激光联合Q开关Nd:YAG激光治疗黄褐斑的疗效观察
Clinical Observation of Non-ablative 1 550nm Fractional Photothermolysis Combined with Q-switch Nd:YAG Laser in the Treatment of Melasma
摘要
Abstract
Objective To investigate the efficacy and safety of a nonablative 1550nm fractional photothermolysis(NFP)combined with a large spot-size,low-fluence Q-Switched neodymium-doped yttrium aluminum garnet(Nd:YAG)laser in treatment of melasma.Methods This is a split-face,randomized,observer-blinded study.In which 19 patients were treated with large spot-size,low-fluence QSNY for 10 sessions at 2-week intervals to the entire faces,and with the 1 550nm NFP for 4 sessions at 6-week intervals to the experimental face.Efficacy variables were Melasma Area and Severity Index(MASI),the physician's global assessment(PGA).Safety was evaluated through the reporting adverse events.Results The percentage of subjective improvement was virtually identical on both sides.Both in terms the degree of improvement and the lack of difference between the QNSY+NFP and QSNY treated sides.No serious side effects were reported in either side.Conclusion Our findings do not support the hypothesis of NFP providing a substantial benefit in treating the melasma when compared with the lone treatment of large spot-size,low-fluence 1064 QSNY.关键词
黄褐斑/Q开关Nd∶YAG激光/点阵激光Key words
melasma/Q-switched Nd: YAG laser/fractional photothermolysis分类
医药卫生引用本文复制引用
吴磊,蔡美红,陈小建,陈玲玲,黄献琛,师逢..1550nm非剥脱性点阵激光联合Q开关Nd:YAG激光治疗黄褐斑的疗效观察[J].中国美容医学,2017,26(12):87-90,4.基金项目
国家自然科学基金青年基金(81500385) （81500385）
