中国全科医学2017，Vol.20Issue(36)：4484-4488,5.DOI:10.3969/j.issn.1007-9572.2017.00.191
维吾尔族不同年龄结直肠癌患者临床病理特点及预后研究
Clinicopathological Features and Associated Factors for Prognosis in Young and Elderly Uygur Colorectal Cancer Patients
摘要
Abstract
Objective To analyze the clinicopathological features and associated factors for prognosis in young and elderly Uygur colorectal cancer (CRC)patients,in order to offer a reference for clinical practice. Methods A total of 211 Uygur patients with CRC treated in the Affiliated Cancer Hospital of Xinjiang Medical University from January 2005 to December 2010,were enrolled and classified into the young group (n = 141,aged < 60 years)and elderly group (n = 70,aged ≥60 years) . We collected their clinical data 〔occupation, gender, blood type, tumor location, tumor size, degree of differentiation,histological type,gross type,T staging,N staging,M staging,TNM staging and CEA and associated factors for prognosis (metastatic status,recurrence and surgical approach)〕and analyzed the clinicopathological features and prognosis of the two groups. Results The type of occupation,degree of differentiation,histological type,gross type differed significantly between the groups (P < 0. 05 ),whereas distribution of gender,blood type,tumor location,tumor size,T staging,N staging,M staging,TNM staging and level of CEA did not (P > 0. 05). The distribution of metastatic site and surgical approach was found to be significantly different in two groups,while the prevalence rates of metastasis and local recurrence were not (P > 0. 05). There was also a significant difference in the survival curve between the young and elderly groups (χ2 =5. 815,P = 0. 016). Conclusion Compared with elderly Uygur patients with CRC,young Uygur CRC patients are more likely to have moderately and poorly differentiated colorectal adenocarcinoma,mass type CRC,higher possibilities of intrahepatic metastasis and poor prognosis.关键词
结直肠肿瘤/维吾尔族/老年人/青年人/病理状态,体征和症状/预后Key words
Colorectal neoplasms/Uygur nationality/Aged/Young adult/Pathological conditions,signs and symptoms/Prognosis分类
医药卫生引用本文复制引用
帕尔哈提·沙依木,艾孜买提·热合木吐拉,赵泽亮,热西达·加帕尔,艾克热木·玉苏甫..维吾尔族不同年龄结直肠癌患者临床病理特点及预后研究[J].中国全科医学,2017,20(36):4484-4488,5.基金项目
新疆维吾尔自治区自然科学基金资助项目(2014211C111) （2014211C111）
