摘要
Abstract
Objective To study on the effects of pelvic autonomic nerve preservation on the long term prognosis and reproductive and urinary function of patients with early cervical cancer. Method From January 2014 to December 2015, 80 cases of early cervical cancer in Shanghai Sixth People's Hospital were studied. The patients were randomly divided into control group and observation group, 40 cases in each group. Control group patients were treated with traditional extensive hysterectomy, while observation group patients were treated with pelvic autonomic nerve preservation. The operation and postoperative complications of the two groups were compared, and the recurrence rate, sexual function, bladder function and rectal function of the patients were followed up for 1 year. Result The operative time of observation group was significantly longer than control group (P < 0.05), the postoperative anal exhaust time was significantly shorter than control group (P < 0.05). There were no significant differences in the amount of bleeding, the number of lymph node dissection and the days of hospitalization between the two groups (P>0.05). After 1 month of follow-up, there was no significant difference in the incidence of complications between the two groups (P>0.05). After 1 year of follow-up, there was no significant difference in the recurrence rate between the two groups (P > 0.05). 1 year after operation, the scores of sexual desire, sexual arousal, vaginal wet skating, orgasm, sexual satisfaction, and sexual intercourse pain of the two groups were significantly lower than those before operation (P<0.05), and the above scores of observation group were significantly lower than control group (P < 0.05). 1 year after operation, the proportion of bladder emptying difficult, urgent micturition and urinary incontinence, constipation, diarrhea, tenesmus, fecal incontinence occurred in observation group were significantly lower than control group (P < 0.05). Conclusion Compared with traditional surgery, although nerve sparing radical hysterectomy hardly reduce the incidence of postoperative complications and risk of recurrence rate, but it has little influence on the sexual function of patients, can effectively promote the function of bladder and rectal function recovery of patients.关键词
保留盆腔自主神经/子宫切除术/早期宫颈癌/预后/生殖泌尿功能Key words
Pelvic autonomic nerve preservation/Hysterectomy/Early cervical cancer/Prognosis/Genito-urinary function
